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Case Reports
. 2022 Nov 7:28:101744.
doi: 10.1016/j.ajoc.2022.101744. eCollection 2022 Dec.

Glomerella cingulata endophthalmitis

Nathan Gunasekaran  1 , Kenneth R Lee  1 , Andrew W Kam  1   2   3 , Dominic McCall  1   2 , Dale Waring  4 , Season Yeung  1   2 , Adrian T Fung  1   2   5   6
Affiliations
Case Reports

Glomerella cingulata endophthalmitis

Nathan Gunasekaran et al. Am J Ophthalmol Case Rep. .

Abstract

Purpose: To report a case of an exogenous endophthalmitis caused by the fungal species Glomerella cingulata.

Observations: A 71-year-old male presented with an infectious keratitis that evolved into endophthalmitis. Combined cataract extraction and pars plana vitrectomy was performed and the vitreous specimen cultured Glomerella cingulata, a variant of the Colletotrichum gloeosporioides fungal species. Despite early treatment with topical, systemic and intravitreal doses of both voriconazole and amphotericin B, the patient had a poor visual and anatomical outcome.

Conclusions and importance: Glomerella cingulata may rarely cause endophthalmitis with devastating visual outcomes.

Keywords: Colletotrichum gloeosporioides; Endophthalmitis; Glomerella cingulata; Keratitis.

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Conflict of interest statement

The following authors have no financial disclosures: NG, KRL, AWK, DM, DW, SY, ATF.

Figures

Fig. 1
Fig. 1
(A) Anterior segment photo of the patient's right eye on initial presentation showing a temporal area of corneal thinning with an adjacent stromal plaque infiltrate and hypopyon. (B) Two weeks following cataract extraction combined with vitrectomy and intravitreal voriconazole, vancomycin plus ceftazidime, the corneal infiltrate is larger with residual anterior vitreous abscess and hypopyon. (C) Two months post-operatively there is persistent hypotony due to phthisis bulbi; (D) B-scan ultrasonography shows an inoperable total retinal detachment.
Fig. 2
Fig. 2
Histological haematoxylin and eosin stained slides of the enucleated globe showing the total retinal detachment at different sections of the globe. (A) Anterior segment including cornea (fold artefactual) (#), iris (λ), and retinal detachment (<) (x20); (B) anterior segment including the ciliary body (β) and cornea (α) (x20); (C) optic nerve with detached retina projecting into vitreous cavity (*) (x20); and (D) posterior sclera and overlying choroid (^) with retinal detachment (x40).
See this image and copyright information in PMC

References

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