Homing in on homeostatic plasticity
- PMID: 36395749
- DOI: 10.1016/j.neuron.2022.10.033
Homing in on homeostatic plasticity
Abstract
In this issue of Neuron, Orr et al.1 demonstrate a detailed molecular cascade that drives presynaptic homeostatic plasticity and enhances presynaptic vesicle fusion in response to reduced postsynaptic activity. Two large presynaptic signaling complexes are central hubs.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Activation and expansion of presynaptic signaling foci drives presynaptic homeostatic plasticity.Neuron. 2022 Nov 16;110(22):3743-3759.e6. doi: 10.1016/j.neuron.2022.08.016. Epub 2022 Sep 9. Neuron. 2022. PMID: 36087584 Free PMC article.
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