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Review
. 2023 Jan-Feb;17(1):2-10.
doi: 10.1016/j.jcct.2022.11.001. Epub 2022 Nov 8.

Computed tomography imaging for subclinical leaflet thrombosis following surgical and transcatheter aortic valve replacement

Hashrul N Rashid  1 , Ronak Rajani  2 , Jonathon Leipsic  3 , Pál Maurovitch-Horvat  4 , Tiffany Patterson  5 , Simon Redwood  6 , Jack Lee  7 , Harriet Hurrell  8 , Stephen J Nicholls  9 , Arthur Nasis  10 , Sujith Seneviratne  11 , James D Cameron  12 , Bernard Prendergast  13 , Robert P Gooley  14
Affiliations
Review

Computed tomography imaging for subclinical leaflet thrombosis following surgical and transcatheter aortic valve replacement

Hashrul N Rashid et al. J Cardiovasc Comput Tomogr. 2023 Jan-Feb.

Abstract

Subclinical leaflet thrombosis (LT) may occur following surgical and transcatheter aortic valve replacement. Computed tomography (CT) has become an established imaging modality to diagnose subclinical LT following bioprosthetic aortic valve replacement. Even so, there is a limited (but growing) experience in utilizing CT imaging for this indication. This review emphasizes a systematic approach to acquiring and analysing CT imaging for subclinical LT, highlighting evidence surrounding clinical sequelae of subclinical LT and anti-thrombotic implications following diagnosis.

Keywords: Aortic stenosis; Aortic valve replacement; Computed tomography; Leaflet thrombosis; TAVR.

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Conflict of interest statement

Declaration of Competing Interest JL has received institutional core laboratory contracts with Edwards Lifesciences, Medtronic, Abbott, Boston Scientific, PI Cardia, and Conformal. PMH is a shareholder of Neumann Medical Ltd. RPG has received personal fees from Boston Scientific, Medtronic, and Abbott Vascular. The remaining authors have nothing to disclose in relation to this article.

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