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. 2023 Mar;270(3):1211-1214.
doi: 10.1007/s00415-022-11487-z. Epub 2022 Nov 18.

Persistent hiccups as main COVID-19 manifestation with transient cytotoxic lesion of the corpus callosum splenium during the Omicron wave in the post-vaccination era

Celeste Sassi  1   2 , Emel Mehmed  3 , Amir Alkhatib  3 , Mario Alberto Forero-Padilla  3 , Dragan S Goranov  3 , Sylvia Habermann  3 , Sven Rekow  3 , Albert Grüger  3 , Hans-Michael Schmitt  3
Affiliations

Persistent hiccups as main COVID-19 manifestation with transient cytotoxic lesion of the corpus callosum splenium during the Omicron wave in the post-vaccination era

Celeste Sassi et al. J Neurol. 2023 Mar.
No abstract available

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
A-S Neuroradiological features detected in the patient described. A–K CT-Angiography of thorax, head and neck, 5 days post COVID-19 Omicron infection. A Axial-CT-Scan displaying an old left thalamic infarct (blue arrow). B-C Thorax-CT axial and coronal scans, without suggestive features for a COVID-19 Omicron pneumonia. D-K CT-Angiography of head and neck without vessel stenosis or occlusion and nor neuroradiological hallmarks typical for a vasculitis (blue arrows). D Circle of Willis (blue arrow). E Left extracranial carotid artery (blue arrow). F right extracranial carotid artery (blue arrow). G Arteria basilaris (blue arrow). H Left arteria vertebralis (blue arrow). I Right arteria vertebralis (blue arrow). J Anterior pericallosal artery (blue arrow). K Posterior pericallosal artery (blue arrow). L–O axial MRI scans performed 7 days post COVID-19 Omicron infection displaying a round midline lesion in the splenium of the corpus callosum with subtle hyperintensity on fluid attenuated inversion recovery (FLAIR) (L) corresponding to a T2-weighted imaging with restricted diffusion (of ca. 5 x 12 mm) (M) and low signal intensity on apparent diffusion coefficient (ADC) (N) and a very mild hypointense signal on T1-weighted imaging (O) (blue arrows). P–S, axial control MRI scans performed 24 days post COVID-19 Omicron infection presenting a complete resolution of the lesion in the splenium of the corpus callosum in the T2-FLAIR sequences (P) as well as in the T2- Diffusion-weighted imaging (DWI) (Q), on apparent diffusion coefficient (ADC) sequences (R) and on T1-weigted imaging (S) (blue arrows), patient asymptomatic and SARS-CoV-2 Rapid Antigen Test negative
See this image and copyright information in PMC

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