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Review
. 2023 Feb;41(1):1-19.
doi: 10.1016/j.ncl.2022.07.004. Epub 2022 Oct 31.

Insomnia: Personalized Diagnosis and Treatment Options

Kori A Porosnicu Rodriguez  1 , Rachel Marie E Salas  2 , Logan Schneider  3
Affiliations
Review

Insomnia: Personalized Diagnosis and Treatment Options

Kori A Porosnicu Rodriguez et al. Neurol Clin. 2023 Feb.

Abstract

Chronic insomnia is a clinical diagnosis fulfilled by criteria: (a) difficulty initiating or maintaining sleep, (b) inability to sleep despite having adequate opportunities, (c) having negative daytime effects due to lack of sleep, and (d) sleep difficulty not explained by other disorder-with symptoms at least three times per week during a period of 3 months. Cognitive behavioral therapy is considered a first-line treatment but can be supported with pharmacologic or digital therapeutics. When developing a patient's care plan, we should consider a "personomics" approach in which we personalize care plans as a form of sleep precision medicine.

Keywords: Cognitive behavioral therapy; Insomnia; Personomics; Sleep; Somnomics.

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Conflict of interest statement

Disclosure Dr. K.A. Porosnicu Rodriguez has no disclosures. Dr. R.M.E. Salas has the following disclosures: Idorsia, Alliance for Sleep (2022-present); HMP Global, Neurology and Sleep Education Consultant (2021-present); American Medical Association, Health System Science Core Faculty (2021-present); ScholarRX, Editorial Board, Education Consulting (2021-present); UptoDate Chapter-royalty (2016-present). Dr. L. Schneider reports personal fees from Jazz Pharmaceuticals, personal fees from Harmony Biosciences outside the submitted work, and employment at Alphabet, Inc.

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