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Comment
. 2023 Feb;20(2):117-118.
doi: 10.1038/s41423-022-00949-z. Epub 2022 Nov 18.

New mechanism to promote long-term T-cell immunity by telomere transfer from antigen-presenting cells

Meiling Jin  1 , Jian-Dong Huang  2   3   4   5
Affiliations
Comment

New mechanism to promote long-term T-cell immunity by telomere transfer from antigen-presenting cells

Meiling Jin et al. Cell Mol Immunol. 2023 Feb.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Telomere vesicle formation and transfer to T cells. Activation of APCs by ionomycin or the formation of immune synapses with T cells induces the degradation of shelterin, resulting in increased activation of TZAP and telomeric repeat sequences, which are encapsulated into telomere vesicles together with the protein Rad51. T cells acquire telomere vesicles to lengthen their telomeres, promoting their longevity
See this image and copyright information in PMC

Comment on

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