Estimated Glomerular Filtration Rate (eGFR) Slope Assessment as a Surrogate End-point in Cardiovascular trials: Implications, Impediments, and Future Directions
- PMID: 36402218
- DOI: 10.1016/j.cpcardiol.2022.101508
Estimated Glomerular Filtration Rate (eGFR) Slope Assessment as a Surrogate End-point in Cardiovascular trials: Implications, Impediments, and Future Directions
Similar articles
-
Change in Albuminuria and GFR as End Points for Clinical Trials in Early Stages of CKD: A Scientific Workshop Sponsored by the National Kidney Foundation in Collaboration With the US Food and Drug Administration and European Medicines Agency.Am J Kidney Dis. 2020 Jan;75(1):84-104. doi: 10.1053/j.ajkd.2019.06.009. Epub 2019 Aug 28. Am J Kidney Dis. 2020. PMID: 31473020
-
Potential Role and Limitations of Estimated Glomerular Filtration Rate Slope Assessment in Cardiovascular Trials: A Review.JAMA Cardiol. 2022 May 1;7(5):549-555. doi: 10.1001/jamacardio.2021.5151. JAMA Cardiol. 2022. PMID: 34985495 Review.
-
Utility and validity of estimated GFR-based surrogate time-to-event end points in CKD: a simulation study.Am J Kidney Dis. 2014 Dec;64(6):867-79. doi: 10.1053/j.ajkd.2014.08.019. Epub 2014 Oct 31. Am J Kidney Dis. 2014. PMID: 25441440
-
Glomerular filtration rate decline as a surrogate end point in kidney disease progression trials.Nephrol Dial Transplant. 2016 Sep;31(9):1425-36. doi: 10.1093/ndt/gfv269. Epub 2015 Jul 11. Nephrol Dial Transplant. 2016. PMID: 26163881 Review.
-
Importance of glomerular filtration rate change as surrogate endpoint for the future incidence of end-stage renal disease in general Japanese population: community-based cohort study.Clin Exp Nephrol. 2018 Apr;22(2):318-327. doi: 10.1007/s10157-017-1463-0. Epub 2017 Sep 7. Clin Exp Nephrol. 2018. PMID: 28884361 Free PMC article.
Cited by
-
Clinical Implications of Slope of GFR in Clinical Trials of CKD Progression.Clin J Am Soc Nephrol. 2025 May 1;20(5):632-641. doi: 10.2215/CJN.0000000662. Epub 2025 Apr 15. Clin J Am Soc Nephrol. 2025. PMID: 40237639
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials
Miscellaneous