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. 2022 Sep;34(3):184-191.
doi: 10.4314/mmj.v34i3.7.

Health workers' knowledge and practice of Isoniazid preventive treatment guidelines in health facilities in Ebonyi State, Nigeria

Ifeyinwa Chizoba Akamike  1   2 , Ijeoma Nkem Okedo-Alex  1   2 , Chigozie Jesse Uneke  2 , Ugochukwu Chinyem Madubueze  1   3 , Urudinachi Nnenne Agbo  1   2 , Ifeyinwa Maureen Okeke  1   2 , Lawrence Ulu Ogbonnaya  1   2   3
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Health workers' knowledge and practice of Isoniazid preventive treatment guidelines in health facilities in Ebonyi State, Nigeria

Ifeyinwa Chizoba Akamike et al. Malawi Med J. 2022 Sep.

Abstract

Background: Isoniazid preventive therapy is recommended as part of a comprehensive HIV and AIDS care strategy. IPT is used as prophylaxis to reduce the incidence of TB in HIV-infected persons. However, its implementation has been very slow and has been influenced by several factors. This study assessed health workers' knowledge and adherence to Isoniazid Preventive Therapy guidelines.

Methods: This was a cross-sectional study in six health facilities providing HIV care in Ebonyi State using a semi-structured, self-administered questionnaire. Data were collected from 85 health workers working in the HIV clinics. Data were also extracted from 200 patient treatment cards. Data analysis was carried out using SPSS version 20 software. Chi-square statistics and logistic regression were carried out to determine the association between socio-demographic characteristics and knowledge as well as self-reported practice of the guideline.

Result: Slightly over half of the respondents (58.8%) had good knowledge of the guideline, and the majority (75.3%) self-reported that they practiced the guideline. Only 17% of the treatment cards had isoniazid prescribed and only 11% of these had patient adherence assessed. The most common challenges to implementation of the guideline cited by health workers were unavailability of isoniazid, poor awareness, patient non-adherence, poor resources, high pill burden, and lack of training. Being a doctor and more than 3 years duration of work in the clinic were predictors of good knowledge. There was no predictor of practice.

Conclusion: There was good knowledge and practice of the guideline from health worker self-reports, however, review of treatment card showed prescription was low. Further studies to explore and understand why there is such low prescription of INH/IPT to HIV patients despite good knowledge of healthcare professionals are recommended.

Keywords: Guideline; Health provider; Implementation; Nigeria; Tuberculosis prevention.

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References

    1. Federal Ministry of Health Department of public health, Nigeria, author. Guideline for isoniazid preventive therapy. 2014.
    1. Isoniazid Preventive Therapy (IPT) for the Prevention of Tuberculosis in People Living with HIV (e-course) | FHI 360 [Internet] [July 2017]. Available from: https://www.fhi360.org/resource/isoniazid-preventive-therapy-ipt-prevent....
    1. TB in Nigeria - Funding, children, diagnosing TB, HIV/TB-Fact sheets. 2019. [April 2019]. Available from: https://www.tbfacts.org/tb-nigeria/
    1. Tikuye AM, Tikuye AM. Knowledge, attitudes and practices of health care providers towards isoniazide preventive therapy (IPT) provision in Addis Ababa, Ethiopia. University of South Africa; 2013. [Dissertation]
    1. Alarcon E, Bissell K, Boillot F, Caminero JA, Chiang C, Clevenbergh P, et al. Isoniazid preventive therapy for people living with HIV : public health challenges and implementation issues. Int J Tuberc Lung Dis. 2015;13(8):927–935. - PubMed

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