Time-delayed modelling of the COVID-19 dynamics with a convex incidence rate
- PMID: 36406926
- PMCID: PMC9652120
- DOI: 10.1016/j.imu.2022.101124
Time-delayed modelling of the COVID-19 dynamics with a convex incidence rate
Abstract
COVID-19 pandemic represents an unprecedented global health crisis which has an enormous impact on the world population and economy. Many scientists and researchers have combined efforts to develop an approach to tackle this crisis and as a result, researchers have developed several approaches for understanding the COVID-19 transmission dynamics and the way of mitigating its effect. The implementation of a mathematical model has proven helpful in further understanding the behaviour which has helped the policymaker in adopting the best policy necessary for reducing the spread. Most models are based on a system of equations which assume an instantaneous change in the transmission dynamics. However, it is believed that SARS-COV-2 have an incubation period before the tendency of transmission. Therefore, to capture the dynamics adequately, there would be a need for the inclusion of delay parameters which will account for the delay before an exposed individual could become infected. Hence, in this paper, we investigate the SEIR epidemic model with a convex incidence rate incorporated with a time delay. We first discussed the epidemic model as a form of a classical ordinary differential equation and then the inclusion of a delay to represent the period in which the susceptible and exposed individuals became infectious. Secondly, we identify the disease-free together with the endemic equilibrium state and examine their stability by adopting the delay differential equation stability theory. Thereafter, we carried out numerical simulations with suitable parameters choice to illustrate the theoretical result of the system and for a better understanding of the model dynamics. We also vary the length of the delay to illustrate the changes in the model as the delay parameters change which enables us to further gain an insight into the effect of the included delay in a dynamical system. The result confirms that the inclusion of delay destabilises the system and it forces the system to exhibit an oscillatory behaviour which leads to a periodic solution and it further helps us to gain more insight into the transmission dynamics of the disease and strategy to reduce the risk of infection.
Keywords: 34D20; 37N25; 39A60; 92B05; COVID-19; Convex incidence rate; Delay differential equation; SEIR epidemic model; Stability.
© 2022 The Author(s).
Conflict of interest statement
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Figures
Similar articles
-
Global dynamics of a multi-strain SEIR epidemic model with general incidence rates: application to COVID-19 pandemic.Nonlinear Dyn. 2020;102(1):489-509. doi: 10.1007/s11071-020-05929-4. Epub 2020 Sep 8. Nonlinear Dyn. 2020. PMID: 32921921 Free PMC article.
-
A study on COVID-19 transmission dynamics: stability analysis of SEIR model with Hopf bifurcation for effect of time delay.Adv Differ Equ. 2020;2020(1):523. doi: 10.1186/s13662-020-02958-6. Epub 2020 Sep 24. Adv Differ Equ. 2020. PMID: 32989381 Free PMC article.
-
Impact of self-imposed prevention measures and short-term government-imposed social distancing on mitigating and delaying a COVID-19 epidemic: A modelling study.PLoS Med. 2020 Jul 21;17(7):e1003166. doi: 10.1371/journal.pmed.1003166. eCollection 2020 Jul. PLoS Med. 2020. PMID: 32692736 Free PMC article.
-
Forecasting the timeframe of 2019-nCoV and human cells interaction with reverse engineering.Prog Biophys Mol Biol. 2020 Sep;155:29-35. doi: 10.1016/j.pbiomolbio.2020.04.002. Epub 2020 Apr 29. Prog Biophys Mol Biol. 2020. PMID: 32360608 Free PMC article. Review.
-
Universal screening for SARS-CoV-2 infection: a rapid review.Cochrane Database Syst Rev. 2020 Sep 15;9(9):CD013718. doi: 10.1002/14651858.CD013718. Cochrane Database Syst Rev. 2020. PMID: 33502003 Free PMC article.
Cited by
-
Fractional differential equation modeling of the HBV infection with time delay and logistic proliferation.Front Public Health. 2022 Nov 11;10:1036901. doi: 10.3389/fpubh.2022.1036901. eCollection 2022. Front Public Health. 2022. PMID: 36438294 Free PMC article.
-
Optimal time-dependent SUC model for COVID-19 pandemic in India.BMC Infect Dis. 2024 Sep 27;24(1):1031. doi: 10.1186/s12879-024-09961-2. BMC Infect Dis. 2024. PMID: 39333900 Free PMC article.
-
Mathematical Modelling of the Spatial Distribution of a COVID-19 Outbreak with Vaccination Using Diffusion Equation.Pathogens. 2023 Jan 5;12(1):88. doi: 10.3390/pathogens12010088. Pathogens. 2023. PMID: 36678436 Free PMC article.
-
Nonlinear time series analysis of state-wise COVID-19 in Malaysia using wavelet and persistent homology.Sci Rep. 2024 Nov 11;14(1):27562. doi: 10.1038/s41598-024-79002-0. Sci Rep. 2024. PMID: 39528569 Free PMC article.
References
-
- Gomes C. Report of the WHO–China joint mission on coronavirus disease 2019 (COVID-19) Braz J Implantol Health Sci. 2020;2(3)
-
- Tipsri S., Chinviriyasit W. The effect of time delay on the dynamics of an SEIR model with nonlinear incidence. Chaos Solitons Fractals. 2015;75:153–172.
-
- Beretta E., Hara T., Ma W., Takeuchi Y. Global asymptotic stability of an SIR epidemic model with distributed time delay. Nonlinear Anal Theory Methods Appl. 2001;47(6):4107–4115.
Publication types
LinkOut - more resources
Full Text Sources
Miscellaneous