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. 2022 Nov 10:2022:1673572.
doi: 10.1155/2022/1673572. eCollection 2022.

The Value of Neutrophil/Lymphocyte Ratio Combined with Red Blood Cell Distribution Width in Evaluating the Prognosis of Emergency Patients with Sepsis

Maosheng Lin  1 , Louwei Zhang  1 , Xuhua Tang  1 , Yejiang Tang  1
Affiliations

The Value of Neutrophil/Lymphocyte Ratio Combined with Red Blood Cell Distribution Width in Evaluating the Prognosis of Emergency Patients with Sepsis

Maosheng Lin et al. Emerg Med Int. .

Abstract

Sepsis is a dysfunction of various organs caused by a dysfunctional host response induced by infection. In recent years, the mortality rate of sepsis patients, especially the mortality rate of septic shock patients still remains high. Due to the complexity and heterogeneity of sepsis, there is currently a lack of clinical biomarkers that can be widely used for the early assessment of sepsis. In order to find more concise and accurate biomarkers for timely and adequate intervention in sepsis, we explored the value of neutrophil/lymphocyte ratio (NLR) combined with red blood cell distribution width (RDW) in assessing the prognosis of emergency sepsis patients. The results showed that NLR and RDW were closely related to the prognosis of emergency sepsis patients. The combination of the two can evaluate the prognosis of patients with emergency sepsis, which deserves close attention from clinicians.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
ROC curve of prognostic value of NLR, RDW, and the combination of the two indexes in emergency sepsis patients.
See this image and copyright information in PMC

References

    1. Olejarova M., Dobisova A., Suchankova M., et al. Vitamin D deficiency—a potential risk factor for sepsis development, correlation with inflammatory markers, SOFA score and higher early mortality risk in sepsis. Bratislava Medical Journal . 2019;120(04):284–290. doi: 10.4149/bll_2019_040. - DOI - PubMed
    1. Madushani R. W. M. A., Patel V., Bihorac A. Early biomarker signatures in surgical sepsis. Journal of Surgical Research . 2022;12(3):125–138. - PMC - PubMed
    1. Hammond N. E., Kumar A., Venkatesh B. Estimates of sepsis prevalence and outcomes in adult patients in the ICU in India: a cross-sectional study. Chest . 2022;31(1):96–118. - PubMed
    1. Kim J., Kim K., Lee H., Ahn S. Epidemiology of sepsis in Korea: a population-based study of incidence, mortality, cost and risk factors for death in sepsis. Clinical and Experimental Emergency Medicine . 2019;6(1):49–63. doi: 10.15441/ceem.18.007. - DOI - PMC - PubMed
    1. Kopczynska M., Sharif B., Cleaver S., et al. Red-flag sepsis and SOFA identifies different patient population at risk of sepsis-related deaths on the general ward. Medicine (Baltimore) . 2018;97(49) doi: 10.1097/md.0000000000013238.13238 - DOI - PMC - PubMed

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