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Review
. 2022 Oct;14(10):395-399.
doi: 10.14740/jocmr4792. Epub 2022 Oct 28.

Type 5 Cardiorenal Syndrome: An Underdiagnosed and Underrecognized Disease Process of the American Mother

Justin Ilagan  1 , Harshini Sahani  2 , Arif Bin Saleh  1 , Kameron Tavakolian  1 , Anton Mararenko  1 , Ndausung Udongwo  1 , Steven Douedi  1 , Vandan Upadhyaya  3 , Swapnil Patel  1 , Arman Mushtaq  1 , Brett Sealove  3 , David Gonzalez  4 , Arif Asif  1
Affiliations
Review

Type 5 Cardiorenal Syndrome: An Underdiagnosed and Underrecognized Disease Process of the American Mother

Justin Ilagan et al. J Clin Med Res. 2022 Oct.

Abstract

Cardiorenal syndrome (CRS) continues to be an area of concern due to the changing understanding of identification, pathophysiology and optimal management. Originally thought that diuretics were always the answer, recent literature has shed lights on the five major CRS subphenotypes, and while conceptual in their classifications, different strategies may be utilized to manage each type. The effect of CRS in pregnant women is largely under discussed and underappreciated as its own entity. Trials involving possible management, specifically utilizing serelaxin, a recombinant form of relaxin, have shown promising results but more data are needed to begin implementing it on a large scale.

Keywords: Cardiorenal syndrome; Pregnant women; Serelaxin; Type 5.

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Conflict of interest statement

None to declare.

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