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Case Reports
. 2022 Oct 18;14(10):e30433.
doi: 10.7759/cureus.30433. eCollection 2022 Oct.

A Case of Supplement-Induced Hepatitis

Affiliations
Case Reports

A Case of Supplement-Induced Hepatitis

Carolina M Pusec et al. Cureus. .

Abstract

Acute hepatitis is an uncommon sequela of herbal supplement use. Regardless, considering the hepatotoxic effects of natural supplements is important, especially in patients taking other medications or substances. We herein describe a case of acute steatohepatitis in a patient who chronically consumed high doses of ashwagandha and other herbal supplements in the context of alcohol use and a multi-medication regimen.

Keywords: acute hepatitis; ashwagandha; hepatitis; herbal supplements; steatohepatitis.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Liver biopsy with hematoxylin and eosin stain at 200x magnification.

References

    1. Wachtel-Galor S, Benzie IFF. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton, Florida: CRC Press/Taylor & Francis; 2011. Herbal medicine: an introduction to its history, usage, regulation, current trends, and research needs. - PubMed
    1. Safety of herbal supplements: a guide for cardiologists. Cohen PA, Ernst E. Cardiovasc Ther. 2010;28:246–253. - PubMed
    1. Prevalence of polypharmacy, polyherbacy, nutritional supplement use and potential product interactions among older adults living on the United States-Mexico border: a descriptive, questionnaire-based study. Loya AM, González-Stuart A, Rivera JO. Drugs Aging. 2009;26:423–436. - PubMed
    1. Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States. Qato DM, Alexander GC, Conti RM, Johnson M, Schumm P, Lindau ST. JAMA. 2008;300:2867–2878. - PMC - PubMed
    1. Alcohol and medication interactions. Weathermon R, Crabb DW. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761694/ Alcohol Res Health. 1999;23:40–54. - PMC - PubMed

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