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Case Reports
. 2022 Nov 2:12:1027504.
doi: 10.3389/fonc.2022.1027504. eCollection 2022.

Alveolar rhabdomyosarcoma of epididymis: A case report

Xiangyi Liang  1 , Shun Wang  1 , Tao Li  1 , Longlong Liu  1 , Yu Duan  1 , Yuting Luo  1 , Qing Wang  1 , Jianxin Hu  1 , Kehua Jiang  1
Affiliations
Case Reports

Alveolar rhabdomyosarcoma of epididymis: A case report

Xiangyi Liang et al. Front Oncol. .

Abstract

Rhabdomyosarcoma (RMS) is a soft tissue tumor, which is the most common in the head, neck, limbs, and trunk. RMS originating from the epididymis is extremely rare. Herein, we reported a 34-year-old patient with RMS on the right epididymis. For this case, right epididymal mass resection was performed and intraoperative freezing suggested a malignant tumor. Right testicular radical resection was subsequently adopted, with right epididymal alveolar RMS being pathologically diagnosed. Alternating VAC/VI chemotherapy was given after surgery, and tumor recurrence has not been found so far.

Keywords: alveolar; diagnosis; epididymis; rhabdomyosarcoma; treatment.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Imaging presentation and gross specimen of a patient with primary eRMS. (A) CT plain scan showed the enlarged and inhomogeneous density of the right testicle; (B) (arterial phase) and (C) (venous phase): CT enhanced scan showed inhomogeneous enhancement of the occupying lesion; (D) General observation.
Figure 2
Figure 2
Microscopic pathology of primary eRMS. (A) Heterotypic cells were seen between the tissues of the right epididymis; (B) tumor size was about 3.5×3.2×2.5 cm; (C) Desmin (+); (D) Myogenin (+).
See this image and copyright information in PMC

References

    1. Kim Y, Huh J, CL H. Kim SD: A case of pediatric paratesticular rhabdomyosarcoma with epididymitis. World J men's Health (2012) 30(2):146–9. doi: 10.5534/wjmh.2012.30.2.146 - DOI - PMC - PubMed
    1. Nakagawa R, Aoyama S, Urata S, Ofude M, Miyagi T, Nakashima T, et al. Testicular rhabdomyosarcoma after chemotherapy for metastatic germ cell tumors. International cancer conference journal (2019) 8:175–80. doi: 10.1007/s13691-019-00378-2 - DOI - PMC - PubMed
    1. Ishiguro N, Motoi T, Osaki M, Araki N, Minamizaki T, Moriyama M, et al. Immunohistochemical analysis of a muscle ankyrin-repeat protein, arpp, in paraffin-embedded tumors: evaluation of arpp as a tumor marker for rhabdomyosarcoma. Human pathology, (2005) 36:620–5. doi: 10.1016/j.humpath.2005.04.014 - DOI - PubMed
    1. Kumar S, Perlman E, CA H, Raffeld M, Tsokos M. Myogenin is a specific marker for rhabdomyosarcoma: an immunohistochemical study in paraffin-embedded tissues. Modern Pathol an Off J United States Can Acad Pathol Inc (2000) 13(9):988–93. doi: 10.1038/modpathol.3880179 - DOI - PubMed
    1. Boudahna L, Benbrahim Z, Amaadour L, Mazouz A, Benhayoune K, Tahiri Y, et al. Para testicular rhabdomyosarcoma in adults: three case reports and review of literature. The Pan African medical journal, (2014) 19:279. doi: 10.11604/pamj.2014.19.279.4784 - DOI - PMC - PubMed

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