Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Dec 15;11(12):e0096122.
doi: 10.1128/mra.00961-22. Epub 2022 Nov 21.

Mycobacteriophage Tarkin: a Cluster E Phage

Katherine E Cleary  1 , Anna M Fakhri  1 , Ethan N Dionne  1 , Marcie Warner  2 , Joseph A DeGiorgis  3   4 , Kathleen Cornely  1
Affiliations

Mycobacteriophage Tarkin: a Cluster E Phage

Katherine E Cleary et al. Microbiol Resour Announc. .

Abstract

Mycobacteriophage Tarkin is a newly isolated phage that infects Mycobacterium smegmatis mc2155. Tarkin was discovered in Providence, RI, and has a 75,998-bp genome sequence. Tarkin is predicted to have 142 protein coding genes and 2 tRNA genes. Based on gene content similarity, Tarkin is grouped with mycobacteriophages in cluster E.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

FIG 1
FIG 1
Image of Tarkin created using a JEOL 200CX transmission electron microscope. Electron microscopy revealed that Tarkin is a member of the Siphoviridae family, with a circular capsid of 75 to 85 nm and a straight tail 235 to 275 nm long.
See this image and copyright information in PMC

Similar articles

  • Genome Sequence of Mycobacterium Phage CrystalP.
    Fleischacker CL, Segura-Totten M; SEA-PHAGES 2016 Bioinformatics Workshop; Garlena RA, Jacobs-Sera D, Pope WH, Russell DA, Hatfull GF. Fleischacker CL, et al. Genome Announc. 2017 Jul 13;5(28):e00542-17. doi: 10.1128/genomeA.00542-17. Genome Announc. 2017. PMID: 28705967 Free PMC article.
  • Genome Sequence of a Newly Isolated Mycobacteriophage, ShedlockHolmes.
    Pope WH, Carter JT, Dasher KL, Haynberg MC, Reddi A, Shedlock KA, Lapin JS, Prout AK, Grubb SR, Warner MH, Bowman CA, Russell DA, Hatfull GF. Pope WH, et al. Genome Announc. 2015 Jun 18;3(3):e00597-15. doi: 10.1128/genomeA.00597-15. Genome Announc. 2015. PMID: 26089412 Free PMC article.
  • Complete genome sequence analysis of the novel mycobacteriophage Shandong1.
    Fan X, Gao X, Wang Q, Shen J, Zhou L, Xie J. Fan X, et al. Arch Virol. 2017 Dec;162(12):3903-3905. doi: 10.1007/s00705-017-3534-7. Epub 2017 Aug 21. Arch Virol. 2017. PMID: 28828700
  • Genome Sequence of Mycobacteriophage Momo.
    Pope WH, Bina EA, Brahme IS, Hill AB, Himmelstein PH, Hunsicker SM, Ish AR, Le TS, Martin MM, Moscinski CN, Shetty SA, Swierzewski T, Iyengar VB, Kim H, Schafer CE, Grubb SR, Warner MH, Bowman CA, Russell DA, Hatfull GF. Pope WH, et al. Genome Announc. 2015 Jun 18;3(3):e00601-15. doi: 10.1128/genomeA.00601-15. Genome Announc. 2015. PMID: 26089415 Free PMC article.
  • On the nature of mycobacteriophage diversity and host preference.
    Jacobs-Sera D, Marinelli LJ, Bowman C, Broussard GW, Guerrero Bustamante C, Boyle MM, Petrova ZO, Dedrick RM, Pope WH; Science Education Alliance Phage Hunters Advancing Genomics And Evolutionary Science Sea-Phages Program; Modlin RL, Hendrix RW, Hatfull GF. Jacobs-Sera D, et al. Virology. 2012 Dec 20;434(2):187-201. doi: 10.1016/j.virol.2012.09.026. Epub 2012 Oct 22. Virology. 2012. PMID: 23084079 Free PMC article. Review.
See all similar articles

References

    1. Jordan TC, Burnett SH, Carson S, Caruso SM, Clase K, DeJong RJ, Dennehy JJ, Denver DR, Dunbar D, Elgin SCR, Findley AM, Gissendanner CR, Golebiewska UP, Guild N, Hartzog GA, Grillo WH, Hollowell GP, Hughes LE, Johnson A, King RA, Lewis LO, Li W, Rosenzweig F, Rubin MR, Saha MS, Sandoz J, Shaffer CD, Taylor B, Temple L, Vazquez E, Ware VC, Barker LP, Bradley KW, Jacobs-Sera D, Pope WH, Russell DA, Cresawn SG, Lopatto D, Bailey CP, Hatfull GF. 2014. A broadly implementable research course in phage discovery and genomics for first-year undergraduate students. mBio 5:e01051-13. doi:10.1128/mBio.01051-13. - DOI - PMC - PubMed
    1. Dedrick R, Guerrero-Bustamante CA, Garlena RA, Russell DA, Ford K, Harris K, Gilmour KC, Soothill J, Jacobs-Sera D, Schooley RT, Hatfull GF, Spencer H. 2019. Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus. Nat Med 25:730–733. doi:10.1038/s41591-019-0437-z. - DOI - PMC - PubMed
    1. Little JS, Dedrick RM, Freeman KG, Cristinziano M, Smith BE, Benson CA, Jhaveri TA, Baden LR, Solomon DA, Hatfull GF. 2022. Bacteriophage treatment of disseminated cutaneous Mycobacterium chelonae infection. Nat Commun 13:2313. doi:10.1038/s41467-022-29689-4. - DOI - PMC - PubMed
    1. Poxleitner M, Pope W, Jacobs-Sera D, Sivanathan V, Hatfull G. 2018. Phage discovery guide. Howard Hughes Medical Institute, Chevy Chase, MD.
    1. Spada S. 2020. Methods to purify DNA from extracellular vesicles: focus on exosomes, p 109–118. In Spada S, Galluzzi L (ed), Methods in Enzymology, vol 645. Academic Press, Cambridge, MA. - PubMed

LinkOut - more resources