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. 2022 Nov 21;17(11):e0277703.
doi: 10.1371/journal.pone.0277703. eCollection 2022.

Evaluation of angle-to-angle and spur-to-spur using swept source optical coherence tomography in different refractive error

Jeong Seop Yun  1 , Ji Sang Min  2 , Kook Young Kim  3
Affiliations

Evaluation of angle-to-angle and spur-to-spur using swept source optical coherence tomography in different refractive error

Jeong Seop Yun et al. PLoS One. .

Abstract

Purpose: To measure angle-to-angle (ATA) and spur-to-spur (STS) distances along six meridians using swept-source optical coherence tomography (SS-OCT) and compare with horizontal white-to-white (WTW) distance in different refractive error.

Methods: Overall, 126 eyes were assessed with the Anterion SS-OCT (Heidelberg Engineering, Heidelberg, Germany). ATA and STS distances were obtained using SS-OCT at 0, 30, 60, 90, 120, and 150 degrees. WTW was measured at 0 degree with built-in infrared camera. One way ANOVA test, pearson correlation coefficient, and stepwise multivariate regression analysis were used to compare ATA and STS distances with age, anterior chamber depth (ACD), axial length (AL), and simulated keratometric values (Sim K) in different refractive error groups.

Results: The mean MRSE refraction was +0.05 ± 0.23 D in the emmetropic group (41 eyes), -3.42 ± 3.04 D in the myopic group (44 eyes), and +1.33 ± 0.64 D in the hyperopic group (31 eyes). There was no statistical difference in the WTW of the emmetropic (11.62 ± 0.44 mm), myopic (11.79 ± 0.46 mm), and hyperopic groups (11.80 ± 0.49 mm) using one-way ANOVA (p = 0.007). ATA and STS were vertically oval in all groups. The correlation between ATA, STS and age, ACD, AL, and K values showed different significance for each meridian according to the refractive error. ATA increased as the horizontal WTW, ACD, and AL increased and Sim K decreased. STS shows relatively smaller explanatory power than ATA in the stepwise multivariate regression analysis.

Conclusions: This study is the first to analyze the relationship between ATA and STS compared to WTW by different refractive error. The difference between the horizontally oval WTW and vertically oval anterior chamber can be large, especially in myopia. ATA showed a greater positive correlation than STS with AL and ACD.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. White to white, spur to spur, and angle to angle distances at the 0 degree (horizontal) meridian, and 6 meridians measured with the anterion swept source optical coherence tomography.
Fig 2
Fig 2. Angle to angle (blue lines) and spur to spur (red line) distances measured at the different meridians.
Horizontal white to white was added and shown as orange lines for comparison. Radial axis starts at 5 mm. Diff. means the difference in value between the ATA and the STS.
Fig 3
Fig 3. Scatter plots showing the relationship between angle to angle (ATA) and spur to spur (STS) versus manifest refractive spherical error (MRSE) in study population (126 eyes).
See this image and copyright information in PMC

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