Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Nov 21;17(11):e0276465.
doi: 10.1371/journal.pone.0276465. eCollection 2022.

Knowledge, attitude, and uptake of human papilloma virus vaccine and associated factors among female preparatory school students in Bahir Dar City, Amhara Region, Ethiopia

Etenesh Adela Lakneh  1 , Eleni Admassu Mersha  2 , Melash Belachew Asresie  2 , Habtamu Gebrehana Belay  3
Affiliations

Knowledge, attitude, and uptake of human papilloma virus vaccine and associated factors among female preparatory school students in Bahir Dar City, Amhara Region, Ethiopia

Etenesh Adela Lakneh et al. PLoS One. .

Abstract

Background: The human papillomavirus vaccine is one of the main preventative measures for cervical cancer. However, global vaccine uptake is low; the problem is particularly acute in low and middle-income countries. The purpose of this study is to assess female preparatory school students' knowledge, attitude, and uptake of the human papillomavirus vaccine and associated factors in Bahir Dar City, Ethiopia.

Methods: Institutional-based cross-sectional study was conducted among 633 female preparatory school students in Bahir Dar city from March 1-30, 2021. Participants were selected using the multistage sampling technique. Data were collected using a structured self-administered questionnaire and entered into Epi-data and exported to SPSS for analysis. Binary and multivariable logistic regression analyses were done using an odds ratio with a 95% confidence interval. Finally-value < 0.05 was considered significant in multivariable analysis.

Result: The proportion of Human Papillomavirus (HPV) vaccine uptake, knowledge of the vaccine, and respondents' attitudes toward the vaccine were 45.3% (95% CI = 41.6-49.4%), 58.1% (95% CI = 54.4-61.9%), and 16% (95% CI = 13.2-19.5%), respectively. Having a history of sexual contact AOR = 2.80 (95% CI = 1.64-4.76), hearing about HPV infection AOR = 1.59 (95% CI = 1.13-2.24), and having a positive attitude toward HPV vaccine AOR = 1.46 (95% CI = 1.03-2.08) were significantly associated with knowledge about the HPV vaccine. Discussion of reproductive health issues with family AOR = 2.558 (95%CI = 1.800-3.636), and having good knowledge about HPV vaccine AOR = 3.571(95%CI = 2.494-5.113) were associated with a positive attitude toward the HPV vaccine. Good knowledge AOR = 2.36(95%CI = 1.48-3.76) and a positive attitude toward HPV vaccine AOR = 2.87(95%CI = 1.70-4.85) were strongly associated with HPV vaccine utilization.

Conclusion: In this study, there was a very low uptake of HPV vaccination among female students, and only a small proportion of them had good knowledge of the HPV vaccine and a favorable attitude toward the HPV vaccine.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Source of information about HPV vaccine, Bahir Dar, Ethiopia, 2021.
Fig 2
Fig 2. Knowledge of respondents about HPV vaccine, Bahir Dar, Ethiopia, 2021.
Fig 3
Fig 3. Uptake of HPV vaccine among female preparatory school students, Bahir Dra, Ethiopia, 2021.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Okunade K.S., Human papillomavirus and cervical cancer. Journal of Obstetrics and Gynaecology, 2020. 40(5): p. 602–608. doi: 10.1080/01443615.2019.1634030 - DOI - PMC - PubMed
    1. Mattiuzzi C. and Lippi G., Cancer statistics: a comparison between world health organization (WHO) and global burden of disease (GBD). European journal of public health, 2020. 30(5): p. 1026–1027. doi: 10.1093/eurpub/ckz216 - DOI - PubMed
    1. FMoH, E., National Cancer Control Plan 2016–2020. Addis Ababa DISEASE PREVENTION AND CONTROL DIRECTORATE, editor. DIRECTORATE DPAC, 2015.
    1. Federal Ministry of Health Ethiopia. National Cancer Control Plan 2016–2020. https://www.iccp-portal.org/sites/default/files/plans/NCCP%20Ethiopia%20... Accessed June 18, 2019.
    1. Weaver BA. Epidemiology and natural history of genital human papillomavirus infection. J Am Osteopath Assoc. 2006;106(3 suppl 1):S2–S8. - PubMed

Substances