Interdisciplinary care of children with diffuse midline glioma
- PMID: 36410226
- PMCID: PMC9676429
- DOI: 10.1016/j.neo.2022.100851
Interdisciplinary care of children with diffuse midline glioma
Abstract
Diffuse Midline Glioma (DMG) which includes Diffuse Intrinsic Pontine Glioma (DIPG) is an infiltrative tumor of the midline structures of the central nervous system that demonstrates an aggressive pattern of growth and has no known curative treatment. As these tumors progress, children experience ongoing neurological decline including inability to ambulate, swallow and communicate effectively. We propose that optimal care for patients with DMG should involve a specialized team experienced in caring for the multifaceted needs of these patients and their families. Herein we review the roles and evidence to support early involvement of a specialized interdisciplinary team and outline our views on best practices for these challenging tumors.
Keywords: Best practices; DIPG; Diffuse Midline glioma; Interdisciplinary care.
Copyright © 2022. Published by Elsevier Inc.
Conflict of interest statement
Declaration of Competing Interest The authors have declared that no conflict of interest exists.
Figures
References
-
- Schwartzentruber J, Korshunov A, Liu X-Y, et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature. 2012;482(7384):226–231. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Research Materials
