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Review
. 2023 Feb;34(1):265-274.
doi: 10.1016/j.pmr.2022.08.015. Epub 2022 Oct 18.

Orthobiologic Techniques for Surgical Augmentation

Kenneth M Lin  1 , Christopher S Frey  1 , Ran Atzmon  1 , Kinsley Pierre  1 , Monica S Vel  1 , Seth L Sherman  2
Affiliations
Review

Orthobiologic Techniques for Surgical Augmentation

Kenneth M Lin et al. Phys Med Rehabil Clin N Am. 2023 Feb.

Abstract

General awareness and clinical utilization of orthobiologic therapy has increased sharply in the recent years. Orthobiologics can be defined as "biological materials and substrates that promote bone, ligament, muscle, and tendon healing." There are 3 major strategies by which orthobiologics are thought to augment tissue repair or native biologic potential: factor-based, cell-based, and biomechanical augmentation. The purpose of this review is to synthesize the recent literature on orthobiologic techniques for surgical augmentation, with focus on several key areas including meniscus repair, osteochondral grafting, and rotator cuff repair.

Keywords: Cell-based augmentation; LR-PRP; Orthobiologics; PRP; Tissue healing.

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Conflict of interest statement

Conflict of interest All authors declare that they have no conflict of interest.