Comment
doi: 10.1016/j.devcel.2022.11.001.
BMPing up endocardial angiogenesis to generate coronary vessels
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- PMID: 36413947
- DOI: 10.1016/j.devcel.2022.11.001
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Comment
BMPing up endocardial angiogenesis to generate coronary vessels
Dev Cell.
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Free article
Abstract
Understanding how coronary vessels develop is important for designing better strategies to repair ischemic hearts. In this issue of Developmental Cell, D'Amato et al. report that BMP2 and CXCL12/CXCR4 act sequentially on endocardial cells to drive coronary angiogenesis and artery morphogenesis.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4.Dev Cell. 2022 Nov 21;57(22):2517-2532.e6. doi: 10.1016/j.devcel.2022.10.007. Epub 2022 Nov 7. Dev Cell. 2022. PMID: 36347256 Free PMC article.
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