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Case Reports
. 2022 Nov 18;10(11):e4655.
doi: 10.1097/GOX.0000000000004655. eCollection 2022 Nov.

Rosacea Aggravated after Intracutaneous Injection of Poly-L-lactic Acid through a Stamp-type Microneedle

Sa Yu  1 , Ruicheng Gong  2 , Lu Wang  2
Affiliations
Case Reports

Rosacea Aggravated after Intracutaneous Injection of Poly-L-lactic Acid through a Stamp-type Microneedle

Sa Yu et al. Plast Reconstr Surg Glob Open. .

Abstract

Injectable poly-L-lactic acid (PLLA) has been widely used for skin texture improvement, volume augmentations of the face or body, and other cosmetic or reconstructive treatment. Despite its significant efficacy, many side effects have also been reported. Here, we describe a case of rosacea aggravated by intracutaneous injection of PLLA using a mesogun injector with stamp-type microneedle. After the treatment, the patient exhibited aggravated rosacea symptoms, such as flushing and erythema. A possible mechanism for the exacerbations might be that PLLA stimulated subclinical inflammatory reaction in the skin. We suggest that PLLA injection should be administered more cautiously in patients with rosacea or other inflammatory skin lesions.

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Figures

Fig. 1.
Fig. 1.
August 16, 2021, after oral minocycline for 2 months, CEA score 3 and SSA score 3.
Fig. 2.
Fig. 2.
October 15, 2021, 1 month after facial intradermal injection of botulinum toxin type A and before intracutaneous injection of PLLA, CEA score 2 and SSA score 1.
Fig. 3.
Fig. 3.
October 30, 2021, half a month after facial intradermal injection of PLLA, CEA score 3 and SSA score 3.
Fig. 4.
Fig. 4.
November 29, 2021, one and a half months after facial intradermal injection of PLLA, CEA score 2 and SSA score 1.
See this image and copyright information in PMC

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