Validation and utility of HepG2 xenograft model for hepatocellular carcinoma

Yangmeihui Song^{1

2}, Qiaomiao Lu^{1

2}, Dawei Jiang^{1

2

3}, Xiaoli Lan^{4

5

6}

Affiliations

¹ Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei, China.
² Hubei Key Laboratory of Molecular Imaging, Wuhan, 430022, Hubei, China.
³ Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Wuhan, 430022, Hubei, China.
⁴ Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei, China. xiaoli_lan@hust.edu.cn.
⁵ Hubei Key Laboratory of Molecular Imaging, Wuhan, 430022, Hubei, China. xiaoli_lan@hust.edu.cn.
⁶ Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Wuhan, 430022, Hubei, China. xiaoli_lan@hust.edu.cn.

Comment

Yangmeihui Song et al. Eur J Nucl Med Mol Imaging. 2023 Feb.

. 2023 Feb;50(3):639-641.

doi: 10.1007/s00259-022-06043-w. Epub 2022 Nov 22.

Yangmeihui Song^{1

2}, Qiaomiao Lu^{1

2}, Dawei Jiang^{1

2

3}, Xiaoli Lan^{4

5

6}

¹ Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei, China.
² Hubei Key Laboratory of Molecular Imaging, Wuhan, 430022, Hubei, China.
³ Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Wuhan, 430022, Hubei, China.
⁴ Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei, China. xiaoli_lan@hust.edu.cn.
⁵ Hubei Key Laboratory of Molecular Imaging, Wuhan, 430022, Hubei, China. xiaoli_lan@hust.edu.cn.
⁶ Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Wuhan, 430022, Hubei, China. xiaoli_lan@hust.edu.cn.

No abstract available

Comment on

PET imaging of hepatocellular carcinoma by targeting tumor-associated endothelium using [⁶⁸Ga]Ga-PSMA-617.
Lu Q, Long Y, Fan K, Shen Z, Gai Y, Liu Q, Jiang D, Cai W, Wan C, Lan X. Lu Q, et al. Eur J Nucl Med Mol Imaging. 2022 Oct;49(12):4000-4013. doi: 10.1007/s00259-022-05884-9. Epub 2022 Jun 28. Eur J Nucl Med Mol Imaging. 2022. PMID: 35763056 Free PMC article.

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1. Santos NP, Colaço AA, Oliveira PA. Animal models as a tool in hepatocellular carcinoma research: a review. Tumour Biol. 2017;39(3):1010428317695923. https://doi.org/10.1177/1010428317695923 . - DOI
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1. Li H, Feng Z, Tsang TC, Tang T, Jia X, He X, et al. Fusion of HepG2 cells with mesenchymal stem cells increases cancer-associated and malignant properties: an in vivo metastasis model. Oncol Rep. 2014;32(2):539–47. https://doi.org/10.3892/or.2014.3264 . - DOI