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Review
. 2022 Dec;23(12):1793-1803.
doi: 10.1007/s11864-022-01023-6. Epub 2022 Nov 22.

Current Practice in Carcinoid Heart Disease and Burgeoning Opportunities

Carrie Lenneman  1 , David Harrison  2 , S Lindsey Davis  3 , Lavanya Kondapalli  4
Affiliations
Review

Current Practice in Carcinoid Heart Disease and Burgeoning Opportunities

Carrie Lenneman et al. Curr Treat Options Oncol. 2022 Dec.

Abstract

Cardiac surgery with tricuspid valve and potentially pulmonic valve replacement at an experienced center is currently the most effective strategy available for the treatment of carcinoid heart disease. Cardiac surgery for carcinoid heart disease requires a multidisciplinary team including cardiology, medical oncology, cardiothoracic anesthesia, and cardiac surgery. Without cardiac surgery, morbidity and mortality from carcinoid heart disease is high. Aggressive management of carcinoid before and after cardiac surgery is critical. Over time, though, circulating carcinoid hormones can lead to destruction of prosthetic valves as well, resulting in recurrent right heart failure. Percutaneous options for valve repair may be on the horizon for management of carcinoid heart disease.

Keywords: Carcinoid crisis; Carcinoid heart disease; Carcinoid syndrome; Cardiac surgery; Neuroendocrine tumor; Pulmonic valve disease; Somatostatin analogs; Tricuspid valve disease; Valvular heart disease.

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References

References and Recommended Reading

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
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