Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Nov 20;10(11):e6627.
doi: 10.1002/ccr3.6627. eCollection 2022 Nov.

Malignant fibroma presenting as a hypoglycemia and coma in a 45-year-old male patient: A case report

Affiliations
Case Reports

Malignant fibroma presenting as a hypoglycemia and coma in a 45-year-old male patient: A case report

Muhammad Hanif et al. Clin Case Rep. .

Abstract

Solitary fibrous tumors (SFTs) are a rare group of spindle cell neoplasm of submesothelial origin with malignant potential and can present as hypoglycemia secondary to excess secretion of insulin-like growth factor II (IGF-II) from the tumor. Early diagnosis and treatment are very important in such cases to prevent hypoxic injury to the brain secondary to hypoglycemia. Here, we are presenting a case of a 45-year-old male patient, who presented with recurrent episodes of hypoglycemia spells, and later on, it was diagnosed that hypoglycemic spells were secondary to fibroma.

Keywords: fibroma; hypoglycemia; insulin‐like growth factor II.

PubMed Disclaimer

Figures

FIGURE 1
FIGURE 1
CT abdomen with oral contrast shows a well‐defined oval hypoattenuating mass in the region of descending colon.

References

    1. Klemperer P, Coleman BR. Primary neoplasms of the pleura. A report of five cases. Am J Ind Med. 1992;22(1):1‐31. doi:10.1002/ajim.4700220103 - DOI - PubMed
    1. Wignall OJ, Moskovic EC, Thway K, Thomas JM. Solitary fibrous tumors of the soft tissues: review of the imaging and clinical features with histopathologic correlation. AJR Am J Roentgenol. 2010;195(1):W55‐W62. doi:10.2214/AJR.09.3379 - DOI - PubMed
    1. Gengler C, Guillou L. Solitary fibrous tumour and hemangiopericytoma: evolution of a concept. Histopathology. 2006;48(1):63‐74. doi:10.1111/j.1365-2559.2005.02290.x - DOI - PubMed
    1. England DM, Hochholzer L, McCarthy MJ. Localized benign and malignant fibrous tumors of the pleura. A clinicopathologic review of 223 cases. Am J Surg Pathol. 1989;13(8):640‐658. doi:10.1097/00000478-198908000-00003 - DOI - PubMed
    1. Baldi GG, Stacchiotti S, Mauro V, et al. Solitary fibrous tumor of all sites: outcome of late recurrences in 14 patients. Clin Sarcoma Res. 2013;3:4. doi:10.1186/2045-3329-3-4 - DOI - PMC - PubMed

Publication types

LinkOut - more resources