Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Nov 1:9:1009356.
doi: 10.3389/fsurg.2022.1009356. eCollection 2022.

Braxon®-assisted prepectoral breast reconstruction: A decade later

Franco Bassetto  1 , Laura Pandis  1 , Federico Facchin  1 , Gian Paolo Azzena  1 , Vincenzo Vindigni  1
Affiliations
Review

Braxon®-assisted prepectoral breast reconstruction: A decade later

Franco Bassetto et al. Front Surg. .

Abstract

We are sitting on the cusp of the bioengineered breast era, in which implant-based breast reconstruction is seeing a growing trend and biotechnology research progressively empowers clinical practice. As never before, the choice of biomaterials has acquired great importance for achieving reconstructive outcomes, and the increase in the use of acellular dermal matrices (ADMs) in the field of senology tells us a story of profound upheaval and progress. With the advent of prepectoral breast reconstruction (PPBR), plenty of devices have been proposed to wrap the silicone prosthesis, either completely or partially. However, this has caused a great deal of confusion and dissent with regard to the adoption of feasible reconstructive strategies as well as the original scientific rationale underlying the prepectoral approach. Braxon® is the very first device that made prepectoral implant positioning possible, wrapping around the prosthesis and exerting the proven ADM regenerative potential at the implant-tissue interface, taking advantage of the body's physiological healing mechanisms. To date, the Braxon® method is among the most studied and practiced worldwide, and more than 50 publications confirm the superior performance of the device in the most varied clinical scenarios. However, a comprehensive record of the working of this pioneering device is still missing. Therefore, our aim with this review is to lay a structured knowledge of surgery with BRAXON® and to provide a decision-making tool in the field of PPBR through a complete understanding on the very first device for prepectoral, one decade after its introduction.

Keywords: Braxon®; acellular dermal matrix; biocompatibility; capsular contracture; cost-effectiveness; prepectoral breast reconstruction; radiotherapy; seroma.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Schematic representation of a Braxon® preshaped design and of the prepectoral technique. Figure adapted from Berna et al., 2014.
Figure 2
Figure 2
Key points of the iBAG study.
Figure 3
Figure 3
Breast-specific, three-dimensional shaped Braxon® Fast matrix.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Di Micco R, Santurro L, Lapiana G, Socci D, Zuber V, Cisternino G, et al. Pre-pectoral implant-based breast reconstruction after mastectomy: a narrative review. Ann Breast Surg. (2021):1–19. 10.21037/abs-21-147 - DOI
    1. Homsy A, Rüegg E, Montandon D, Vlastos G, Modarressi A, Pittet B. Breast reconstruction: a century of controversies and progress. Ann Plast Surg. (2018) 80:457–63. 10.1097/SAP.0000000000001312 - DOI - PubMed
    1. Champaneria MC, Wong WW, Hill ME, Gupta SC. The evolution of breast reconstruction: a historical perspective. World J Surg. (2012) 36:730–42. 10.1007/s00268-012-1450-2 - DOI - PubMed
    1. Bennett KG, Qi J, Kim HM, Hamill JB, Pusic AL, Wilkins EG. Comparison of 2-year complication rates among common techniques for postmastectomy breast reconstruction. JAMA Surg. (2018) 153(10):901–8. 10.1001/jamasurg.2018.1687 - DOI - PMC - PubMed
    1. Huang J, Chan PS, Lok V, Chen X, Ding H, Jin Y, et al. Global incidence and mortality of breast cancer. Aging. (2021) 13(4):5748–803. 10.18632/aging.202502 - DOI - PMC - PubMed