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Review
. 2022 Nov 18;12(11):1046.
doi: 10.3390/bios12111046.

Nanomaterials-Based Electrochemiluminescence Biosensors for Food Analysis: Recent Developments and Future Directions

Jiaojiao Zhou  1 , Xuqin Lv  1   2 , Jilai Jia  1 , Zia-Ud Din  3 , Shiqi Cai  1 , Jiangling He  1 , Fang Xie  1 , Jie Cai  1   2
Affiliations
Review

Nanomaterials-Based Electrochemiluminescence Biosensors for Food Analysis: Recent Developments and Future Directions

Jiaojiao Zhou et al. Biosensors (Basel). .

Abstract

Developing robust and sensitive food safety detection methods is important for human health. Electrochemiluminescence (ECL) is a powerful analytical technique for complete separation of input source (electricity) and output signal (light), thereby significantly reducing background ECL signal. ECL biosensors have attracted considerable attention owing to their high sensitivity and wide dynamic range in food safety detection. In this review, we introduce the principles of ECL biosensors and common ECL luminophores, as well as the latest applications of ECL biosensors in food analysis. Further, novel nanomaterial assembly strategies have been progressively incorporated into the design of ECL biosensors, and by demonstrating some representative works, we summarize the development status of ECL biosensors in detection of mycotoxins, heavy metal ions, antibiotics, pesticide residues, foodborne pathogens, and other illegal additives. Finally, the current challenges faced by ECL biosensors are outlined and the future directions for advancing ECL research are presented.

Keywords: biosensors; electrochemiluminescence; food analysis; nanomaterials.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Scheme of the principles of ECL biosensors, ECL luminophores, and their ECL applications in food analysis.
Figure 2
Figure 2
Scheme of ECL process. Reproduced with permission from Ref. [24]. Copyright 2017, Elsevier.
Figure 3
Figure 3
(A) Scheme of bipolar electrode ECL biosensor for OTA detection. Reproduced with permission from Ref. [48]. Copyright 2021, Elsevier. (B) Scheme of ECL aptasensor for OTA detection using a DNA walking machine. Reproduced with permission from Ref. [50]. Copyright 2019, Elsevier.
Figure 4
Figure 4
Scheme of the ECL and colorimetric sensor for Hg2+ detection. Reproduced with permission from Ref. [57]. Copyright 2021, Elsevier.
Figure 5
Figure 5
Scheme of the ECL sensor for kanamycin detection. Reproduced with permission from Ref. [73]. Copyright 2021, American Chemical Society.
See this image and copyright information in PMC

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