Time Trends of Cardiovascular Disease in the General Population and Inflammatory Arthritis

Abstract

Cardiovascular diseases (CVDs) are the leading causes of death in the world, but declining trends for cardiovascular (CV) mortality and morbidity have been observed during the last decades. Reports on secular trends regarding the excess CV mortality and morbidity in rheumatoid arthritis show diverging results. Data support that also patients with inflammatory arthritis have benefited from improved treatment and prevention for CVD, which can be observed, for example, in decreased case fatality after CV event. However, several recent studies indicate a remaining excess CV risk in patients with inflammatory arthritis.

Keywords: Cardiovascular disease; Psoriatic arthritis; Rheumatoid arthritis; Spondarthritis; Time trends.