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The measure of torquetenovirus (TTV) viremia is widely recognized as an optimal biomarker of an individual immune status. In the context of COVID-19, the predictive role of TTV load with regard to vaccine response has also been demonstrated, suggesting other intriguing applications for this widespread anellovirus.
Querido S, Calça R, Weigert A, et al. Kinetics of torquetenovirus DNA load in a recent kidney transplant recipient with mild SARS-CoV-2 infection and a failed antibody response. Transpl Infect Dis. 2021;23:e13524.
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Forqué L, Albert E, Giménez E, et al. Monitoring of Torque Teno virus DNAemia in critically ill COVID-19 patients: may it help to predict clinical outcomes? J Clin Virol. 2022;148
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Solis M, Gallais F, Garnier-Kepka S, et al. Combining predictive markers for severe COVID-19: Torquetenovirus DNA load and SARS-CoV-2 RNAemia. J Clin Virol. 2022;148
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Stincarelli MA, Baj A, Guidotti B, et al. Plasma Torquetenovirus (TTV) microRNAs and severity of COVID-19. Virol J. 2022;19:79.
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Emmel V, Gama B, de Paula A, Ferreira G, Binato R, Abdelhay E. Can Torque teno virus be a predictor of SARS-CoV-2 disease progression in cancer patients? J Infect Chemother: Official J Japan Society of Chemotherapy. 2022;28:1623–1627.
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