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Comment
. 2023 Feb;20(2):67-68.
doi: 10.1038/s41571-022-00712-3.

PADA-1 trial: ESR1 mutations in plasma ctDNA guide treatment switching

Ben O'Leary  1   2
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Comment

PADA-1 trial: ESR1 mutations in plasma ctDNA guide treatment switching

Ben O'Leary. Nat Rev Clin Oncol. 2023 Feb.
No abstract available

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References

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    1. Toy, W. et al. ESR1 ligand-binding domain mutations in hormone-resistant breast cancer. Nat. Genet. 45, 1439–1445 (2013). - DOI
    1. Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature 490, 61–70 (2012). - DOI
    1. Fribbens, C. et al. Plasma ESR1 mutations and the treatment of estrogen receptor-positive advanced breast cancer. J. Clin. Oncol. 34, 2961–2968 (2016). - DOI
    1. Chandarlapaty, S. et al. Prevalence of ESR1 mutations in cell-free DNA and outcomes in metastatic breast cancer: a secondary analysis of the BOLERO-2 clinical trial. JAMA Oncol. 2, 1310–1315 (2016). - DOI

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