Editorial: Extracellular vesicles in cardiovascular inflammation and calcification

Jona B Krohn^{1

2}, Elena Aikawa^{3

4}, Masanori Aikawa^{3

4}, Joshua D Hutcheson^{5

6}, Susmita Sahoo⁷, Jason E Fish^{8

9

10}

Affiliations

¹ Department of Cardiology, Angiology and Pulmonology, University Hospital Heidelberg, Heidelberg, Germany.
² German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg/Mannheim, Heidelberg, Germany.
³ Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
⁴ Center for Excellence in Vascular Biology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
⁵ Department of Biomedical Engineering, Florida International University, Miami, FL, United States.
⁶ Biomolecular Sciences Institute, Florida International University, Miami, FL, United States.
⁷ Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
⁸ Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.
⁹ Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
¹⁰ Peter Munk Cardiac Centre, Toronto General Hospital, University Health Network, Toronto, ON, Canada.

PMID: 36426218
PMCID: PMC9680153
DOI: 10.3389/fcvm.2022.1077124

Editorial

Editorial: Extracellular vesicles in cardiovascular inflammation and calcification

Jona B Krohn et al. Front Cardiovasc Med. 2022.

. 2022 Nov 8:9:1077124.

doi: 10.3389/fcvm.2022.1077124. eCollection 2022.

Authors

Jona B Krohn^{1

2}, Elena Aikawa^{3

4}, Masanori Aikawa^{3

4}, Joshua D Hutcheson^{5

6}, Susmita Sahoo⁷, Jason E Fish^{8

9

10}

Affiliations

¹ Department of Cardiology, Angiology and Pulmonology, University Hospital Heidelberg, Heidelberg, Germany.
² German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg/Mannheim, Heidelberg, Germany.
³ Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
⁴ Center for Excellence in Vascular Biology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
⁵ Department of Biomedical Engineering, Florida International University, Miami, FL, United States.
⁶ Biomolecular Sciences Institute, Florida International University, Miami, FL, United States.
⁷ Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
⁸ Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.
⁹ Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
¹⁰ Peter Munk Cardiac Centre, Toronto General Hospital, University Health Network, Toronto, ON, Canada.

PMID: 36426218
PMCID: PMC9680153
DOI: 10.3389/fcvm.2022.1077124

No abstract available

Keywords: atherosclerosis; calcific aortic valve disease; coronary artery disease; extracellular vesicles (EV); inflammation; vascular calcification.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Comment on

Editorial on the Research Topic Extracellular vesicles in cardiovascular inflammation and calcification

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References

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1. Bakhshian Nik A, Hutcheson JD, Aikawa E. Extracellular vesicles as mediators of cardiovascular calcification. Front Cardiovasc Med. (2017) 4:78. 10.3389/fcvm.2017.00078 - DOI - PMC - PubMed
1. Hutcheson JD, Goettsch C, Bertazzo S, Maldonado N, Ruiz JL, Goh W, et al. . Genesis and growth of extracellular-vesicle-derived microcalcification in atherosclerotic plaques. Nat Mater. (2016) 15:335–43. 10.1038/nmat4519 - DOI - PMC - PubMed
1. Sahoo S, Adamiak M, Mathiyalagan P, Kenneweg F, Kafert-Kasting S, Thum T. Therapeutic and diagnostic translation of extracellular vesicles in cardiovascular diseases: roadmap to the clinic. Circulation. (2021) 143:1426–49. 10.1161/CIRCULATIONAHA.120.049254 - DOI - PMC - PubMed
1. Krohn JB, Hutcheson JD, Martinez-Martinez E, Aikawa E. Extracellular vesicles in cardiovascular calcification: expanding current paradigms. J Physiol. (2016) 594:2895–903. 10.1113/JP271338 - DOI - PMC - PubMed

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Editorial: Extracellular vesicles in cardiovascular inflammation and calcification

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Editorial: Extracellular vesicles in cardiovascular inflammation and calcification

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