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. 2022 Nov 11;19(22):14853.
doi: 10.3390/ijerph192214853.

Inflammatory Biomarker Responses to Whole-Body Vibration in Subjects with Different Clinical Status: A Systematic Review

Eloá Moreira-Marconi  1   2   3 , Ygor Teixeira-Silva  1   3   4 , Alexandre Gonçalves de Meirelles  1   3   5 , Maria Eduarda de Souza Melo-Oliveira  1   5 , Aline Cristina Gomes Santos  1   2 , Aline Reis-Silva  1   4 , Laisa Liane Paineiras-Domingos  1   4   6 , Aderito Seixas  7 , Carla da Fontoura Dionello  8 , Danúbia da Cunha de Sá-Caputo  1   2   4 , Mario Bernardo-Filho  1
Affiliations

Inflammatory Biomarker Responses to Whole-Body Vibration in Subjects with Different Clinical Status: A Systematic Review

Eloá Moreira-Marconi et al. Int J Environ Res Public Health. .

Abstract

Background: Inflammation is considered to be a vital defense mechanism for health, acting as a protective response of the immune system through a satisfactory inflammatory biomarker response (IBR). IBR, as well as being beneficial to the organism, can be also responsible for a variety of chronic inflammatory diseases. Whole-body vibration (WBV) exercise is a type of physical exercise that can act on inflammation responses due its capacity for stimulating the sensory components that promote systemic responses. The objective of this study was to investigate the effects of WBV on IBR in different clinical status.

Methods: This is a systematic review that includes randomized controlled trials (RCTs) on the effects of WBV exercise on IBR. The methodological quality, risk of bias, and level of evidence were rated.

Results: Four RCTs met the selection criteria. The studies showed benefits associated with IBR (e.g., cytokines, adipokines, and C-reactive protein) in various clinical conditions, including healthy populations and some chronic diseases (such as obesity, aging disorders, and knee osteoarthritis), using several WBV protocols.

Conclusions: WBV might be useful in the management of inflammatory conditions.

Keywords: inflammation; physical and rehabilitation medicine; whole-body vibration exercise.

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Conflict of interest statement

The authors declare that there are no conflict of interest (political, personal, religious, ideological, academic, intellectual, commercial, or any other) in relation to this manuscript.

Figures

Figure 1
Figure 1
The PRISMA flowchart.
Figure 2
Figure 2
(a) Risk-of-bias graph and (b) summary indicating the risk of bias of each domain in each study. Green indicates low risk of bias, yellow indicates unclear risk of bias, and red indicates high risk of bias of the studies: Bellia et al., 2013 [40], Rodriguez-Miguelez et al., 2015 [19], Di Giminiani et al., 2020 [41], Simão et al., 2012 [42].
Figure 3
Figure 3
Inflammatory biomarker responses to whole-body vibration intervention in each clinical status.
See this image and copyright information in PMC

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