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Review
. 2022 Nov 15;12(11):1897.
doi: 10.3390/life12111897.

Fine-Needle Aspiration Cytology for Parotid Tumors

Masataka Taniuchi  1 , Tetsuya Terada  1 , Ryo Kawata  1
Affiliations
Review

Fine-Needle Aspiration Cytology for Parotid Tumors

Masataka Taniuchi et al. Life (Basel). .

Abstract

Fine-needle aspiration (FNA) cytology is widely used in clinical practice as a simple and minimally invasive test for parotid tumors that allows for preoperative estimation of benignancy and malignancy, histological type, and malignancy grade and can be performed on an outpatient basis. In recent years, cell blocks prepared with core needle biopsy (CNB) and liquid-based cytology (LBC) have increased the reliability of immunostaining and molecular biological testing, leading to improved diagnostic accuracy. In 2018, the Milan System for Reporting Salivary Gland Cytology was introduced, but it does not include malignancy grade or histological type, so we proposed the Osaka Medical College classification as a more clinically based cell classification that includes both types of information, and we have reported on its usefulness. This review gives an overview of the history and use of FNA and describes CNB and LBC and the two classification systems.

Keywords: cytology; fine-needle aspiration; parotid tumor.

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Conflict of interest statement

The authors declare no conflict of interest.

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References

    1. Stewart C.J., MacKenzie K., McGarry G.W., Mowat A. Fine-needle aspiration cytology of salivary gland: A review of 341 cases. Diagn. Cytopathol. 2000;22:139–146. doi: 10.1002/(SICI)1097-0339(20000301)22:3<139::AID-DC2>3.0.CO;2-A. - DOI - PubMed
    1. Zbären P., Schär C., Hotz M.A., Loosli H. Value of fine-needle aspiration cytology of parotid gland masses. Laryngoscope. 2001;111:1989–1992. doi: 10.1097/00005537-200111000-00023. - DOI - PubMed
    1. Klijanienko J., Vielh P. Fine-needle sampling of salivary gland lesions. II. Cytology and histology correlation of 71 cases of Warthin’s tumor (adenolymphoma) Diagn. Cytopathol. 1997;16:221–225. doi: 10.1002/(SICI)1097-0339(199703)16:3<221::AID-DC5>3.0.CO;2-I. - DOI - PubMed
    1. Ahn S., Kim Y., Oh Y.L. Fine needle aspiration cytology of benign salivary gland tumors with myoepithelial cell participation: An institutional experience of 575 cases. Acta Cytol. 2013;57:567–574. doi: 10.1159/000354958. - DOI - PubMed
    1. Colella G., Cannavale R., Flamminio F., Foschini M.P. Fine-needle aspiration cytology of salivary gland lesions: A systematic review. J. Oral Maxillofac. Surg. 2010;68:2146–2153. doi: 10.1016/j.joms.2009.09.064. - DOI - PubMed

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