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1 Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore.
2 Department of Biostatistics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
3 Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
4 Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore, Singapore.
5 Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
6 Allergy Service, Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore.
7 Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.
8 Folkhälsan Research Center, Helsinki, Finland.
9 Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.
10 Department of Maternal Fetal Medicine, KK Women's and Children's Hospital (KKH), Singapore, Singapore.
11 Duke-NUS Medical School, Singapore, Singapore.
12 Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
13 Endocrinology Service, Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore.
14 School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.
15 NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK.
16 MRC Lifecourse Epidemiology Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
17 Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
1 Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore.
2 Department of Biostatistics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
3 Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
4 Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore, Singapore.
5 Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
6 Allergy Service, Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore.
7 Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.
8 Folkhälsan Research Center, Helsinki, Finland.
9 Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.
10 Department of Maternal Fetal Medicine, KK Women's and Children's Hospital (KKH), Singapore, Singapore.
11 Duke-NUS Medical School, Singapore, Singapore.
12 Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
13 Endocrinology Service, Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore.
14 School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.
15 NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK.
16 MRC Lifecourse Epidemiology Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
17 Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Godfrey KM has received reimbursement for speaking at conferences sponsored by Nestle. Godfrey KM, Chan SY, and Chong YS are part of an academic consortium that has received research funding from Abbot Nutrition, Nestle, and Danone. All other authors declare no conflict of interest.
References
Pike KC, Calder PC, Inskip HM, et al. Maternal plasma phosphatidylcholine fatty acids and atopy and wheeze in the offspring at age of 6 years. Clin Dev Immunol. 2012;2012:474613. doi:10.1155/2012/474613
-
DOI
-
PMC
-
PubMed
Rucci E, den Dekker HT, de Jongste JC, et al. Maternal fatty acid levels during pregnancy, childhood lung function and atopic diseases. The generation R study. Clin Exp Allergy. 2016;46(3):461‐471. doi:10.1111/cea.12613
-
DOI
-
PubMed
Miles EA, Childs CE, Calder PC. Long‐chain polyunsaturated fatty acids (LCPUFAs) and the developing immune system: a narrative review. Nutrients. 2021;13(1):247. doi:10.3390/nu13010247
-
DOI
-
PMC
-
PubMed
Hanebutt FL, Demmelmair H, Schiessl B, Larqué E, Koletzko B. Long‐chain polyunsaturated fatty acid (LC‐PUFA) transfer across the placenta. Clin Nutr. 2008;27(5):685‐693. doi:10.1016/j.clnu.2008.05.010
-
DOI
-
PubMed
Newson RB, Shaheen SO, Henderson AJ, Emmett PM, Sherriff A, Calder PC. Umbilical cord and maternal blood red cell fatty acids and early childhood wheezing and eczema. J Allergy Clin Immunol. 2004;114(3):531‐537. doi:10.1016/j.jaci.2004.05.010
-
DOI
-
PubMed