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Case Reports
. 2022 Nov 26;16(1):443.
doi: 10.1186/s13256-022-03670-7.

Primary ectopic breast carcinoma: a case report

Leila Achouri  1   2 , Amani Jellali  3   4 , Houda Henchiri  5 , Sabrine Boukhris  5   3 , Yosra Zaaimi  3   6 , Houyem Mansouri  5   3 , Najet Mahjoub  5   3
Affiliations
Case Reports

Primary ectopic breast carcinoma: a case report

Leila Achouri et al. J Med Case Rep. .

Abstract

Background: Ectopic breast tissue is present in 2-6% of women. Ectopic mammary tissue can experience physiological changes and the same pathological processes as the eutopic breast. Ectopic breast cancer represents an uncommon condition accounting for 0.3% of all breast neoplasms, and it is most frequently located in the axilla.

Case report: We report a rare case of a 57-year-old Tunisian woman who presented with a left-sided axillary mass evolving for about 1 month. The axillary ectopic breast tissue containing the mass was excised with axillary dissection. Pathology revealed a medullary multifocal carcinoma and metastasis was detected in two lymph nodes. She had local radiotherapy after six cycles of chemotherapy. She received herceptin therapy and hormonotherapy. After a 2-year follow-up, no evidence of local recurrence or distant metastases have been identified.

Conclusion: Ectopic breast carcinoma is a rare entity that should be the first diagnosis to be considered if an axillary lump is present in ectopic breast tissue. No particular guidelines on diagnosis and treatment are available. Therefore, physicians should be aware of this condition to avoid treatment delays. Once diagnosed, careful patient follow-up is essential because of the ambiguous natural history of this rare entity.

Keywords: Breast; Carcinoma; Case report; Ectopic; Management.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Mediolateral oblique mammography view revealing an ectopic breast with an ill-defined opacity
Fig. 2
Fig. 2
Normal bilateral craniocaudal mammography view
Fig. 3
Fig. 3
A Low estrogen labeling (*400); B Absence of labeling for progesterone receptors (*200); C Subcutaneous carcinomatous proliferation (*40); D Carcinomatous masses with comedonecrosis (*40)
See this image and copyright information in PMC

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