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. 2022 Jul-Sep;47(3):425-428.
doi: 10.4103/ijcm.ijcm_743_21. Epub 2022 Oct 10.

Micronutrient Deficiency in Pregnancy: Time to Think Beyond Iron and Folic Acid Supplementation

Muthu Gopal  1 , K Sunitha  2 , J Arockiasamy  3 , Maryam Jamila Sibqathulla  4 , J Yuvaraj  5 , Shantaraman Kalyanaraman  6
Affiliations

Micronutrient Deficiency in Pregnancy: Time to Think Beyond Iron and Folic Acid Supplementation

Muthu Gopal et al. Indian J Community Med. 2022 Jul-Sep.

Abstract

Background: Micronutrients play an important role in influencing pregnancy outcomes. Anemia is common among pregnant women against which iron and folic acid supplementation programs are already in action. The study aimed to estimate the prevalence of anemic and selected micronutrient status among pregnant women.

Materials and methods: It is a community-based cross-sectional study. The study was carried out among pregnant women registered in Primary Health Center, Kallur, Tirunelveli district, Tamil Nadu, India, using a semi-structured data capture tool. The blood samples were collected following standard procedure.

Results: The micronutrient status among 139 pregnant women were selenium <1%, copper <1%, zinc 11.5%, iodine 14.4%, Vitamin B12 41.7%, and ferritin 42.4%. Vitamin B12, zinc, and selenium levels showed a significant difference with reference values among the three trimesters. Iron and folic acid supplementation was followed by 58.7% of pregnant women. Multiple micronutrient deficiency with anemia was found among 54.6%.

Conclusion: Anemia and micronutrient deficiency are high among pregnant women in this region. Since iron and folic acid supplementation strategies are already being implemented by the government, it is high time that we extend our health policy beyond that and plan for micronutrient supplementation as well.

Keywords: Anemia; Vitamin B12; ferritin; micronutrients; pregnancy.

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Conflict of interest statement

There are no conflicts of interest.

References

    1. Kominiarek MA, Rajan P. Nutrition Recommendations in Pregnancy and Lactation. Med Clin North Am. 2016;100:1199–215. - PMC - PubMed
    1. World Health Organization. WHO. [Last accessed on 2020 Nov 26]. Available from: https://www.who.int/nutrition/topics/globaltargets_lowbirthweight_policy... .
    1. Mousa A, Naqash A, Lim S. Macronutrient and micronutrient intake during pregnancy:An Overview of recent evidence. Nutrients. 2019;11:E443. - PMC - PubMed
    1. McCauley ME, Van den Broek N, Dou L, Othman M. Vitamin A supplementation during pregnancy for maternal and newborn outcomes. Cochrane Database Syst Rev. 2015;2015(10):CD00. - PMC - PubMed
    1. Hofstee P, McKeating DR, Perkins AV, Cuffe JS. Placental adaptations to micronutrient dysregulation in the programming of chronic disease. Clin Exp Pharmacol Physiol. 2018;45:871–84. - PubMed