Monkeypox: Clinical Considerations, Epidemiology, and Laboratory Diagnostics

Lucas J Osborn¹, Diana Villarreal^{2

3}, Noah Wald-Dickler^{4

3}, Jennifer Dien Bard^{1

5}

Affiliations

¹ Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California.
² Department of Pediatrics, Maternal Child and Adolescent/Adult Center for Infectious Diseases and Virology, University of Southern California, Los Angeles, California.
³ Department of Medicine and Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California.
⁴ Department of Internal Medicine, Division of Infectious Diseases, University of Southern California, Los Angeles, California.
⁵ Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California.

PMID: 36438980
PMCID: PMC9674185
DOI: 10.1016/j.clinmicnews.2022.11.003

Monkeypox: Clinical Considerations, Epidemiology, and Laboratory Diagnostics

Lucas J Osborn et al. Clin Microbiol Newsl. 2022.

. 2022 Nov 15;44(22):199-208.

doi: 10.1016/j.clinmicnews.2022.11.003. Epub 2022 Nov 18.

Authors

Lucas J Osborn¹, Diana Villarreal^{2

3}, Noah Wald-Dickler^{4

3}, Jennifer Dien Bard^{1

5}

Affiliations

¹ Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California.
² Department of Pediatrics, Maternal Child and Adolescent/Adult Center for Infectious Diseases and Virology, University of Southern California, Los Angeles, California.
³ Department of Medicine and Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California.
⁴ Department of Internal Medicine, Division of Infectious Diseases, University of Southern California, Los Angeles, California.
⁵ Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California.

PMID: 36438980
PMCID: PMC9674185
DOI: 10.1016/j.clinmicnews.2022.11.003

Abstract

Monkeypox virus (MPXV) has garnered recent attention as outbreaks are continually reported outside historic regions of endemicity in Africa. Consequently, MPXV is becoming routinely included in the differential diagnosis of rash illnesses, requiring clinicians and laboratorians alike to quickly adapt to a new public health emergency. This review discusses the epidemiology, clinical presentation, and laboratory testing of MPXV in the context of recent outbreaks.

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References

1. International Committee on Taxonomy of Viruses Current ICTV taxonomy release. https://ictv.global/taxonomy n.d. [accessed 23 August 2022]
1. Loeffelholz MJ, Hodinka RL, Young SA, Pinsky BA. Clinical virology manual. 5th ed. ASM Press; Washington, DC: 2016.
1. Ladnyj ID, Ziegler P, Kima E. A human infection caused by monkeypox virus in Basankusu Territory, Democratic Republic of the Congo. Bull World Health Organ. 1972;46:593–597. - PMC - PubMed
1. Reynolds MG, Damon IK. Outbreaks of human monkeypox after cessation of smallpox vaccination. Trends Microbiol. 2012;20:80–87. doi: 10.1016/j.tim.2011.12.001. - DOI - PubMed
1. Liu L. Fields virology, 6th edition. Clin Infect Dis. 2014;59:613. doi: 10.1093/cid/ciu346. - DOI

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Monkeypox: Clinical Considerations, Epidemiology, and Laboratory Diagnostics

Affiliations

Monkeypox: Clinical Considerations, Epidemiology, and Laboratory Diagnostics

Authors

Affiliations

Abstract

References

LinkOut - more resources

Full Text Sources