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Case Reports
. 2022 Nov 23;10(11):e6538.
doi: 10.1002/ccr3.6538. eCollection 2022 Nov.

Oral propranolol and topical timolol in the treatment of post-burn pyogenic granuloma: Two cases and a review of the literature

Zahra Ebrahimi  1 , Zeinab Mahdi  2 , Ali Asghar Khairi  3 , Elham Behrangi  2   4 , Armaghan Gharehaghaji Zare  5 , Abbas Dehghani  2 , Azadeh Goodarzi  2
Affiliations
Case Reports

Oral propranolol and topical timolol in the treatment of post-burn pyogenic granuloma: Two cases and a review of the literature

Zahra Ebrahimi et al. Clin Case Rep. .

Abstract

Two cases of pyogenic granulomas in burned skin were presented, a 17-month-old boy and a 7-year-old girl, being given oral propranolol and topical timolol. Both cases showed lesions improvement with no adverse effects, suggesting that beta-blocker therapy may have a positive impact on the treatment of pyogenic granuloma after burns.

Keywords: beta‐blocker; burn; hemangioma; oral beta‐blocker; post‐burn hemangioma; post‐burn pyogenic granuloma; propranolol; pyogenic granuloma; therapy; timolol; topical beta‐blocker; treatment.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

FIGURE 1
FIGURE 1
(A–C): Multiple post‐burn pyogenic granulomas specially behind the left ear and on the right elbow. (D): Significant improvement after a 9‐day treatment with oral propranolol and topical timolol.
FIGURE 2
FIGURE 2
(A, B): A red, oozing pyogenic granuloma on the burned skin. (C): A dramatic reduction of the lesion after 2 weeks of treatment. (D): The lesion after treating with beta‐blockers and a 6‐month follow‐up.
See this image and copyright information in PMC

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