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Comment
. 2023 Mar;200(6):691-693.
doi: 10.1111/bjh.18579. Epub 2022 Nov 28.

Treatment response in acute myeloid leukaemia-Clues in the biopsy core

Alicia G Aguilar Navarro  1 , Anastasia N Tikhonova  1
Affiliations
Comment

Treatment response in acute myeloid leukaemia-Clues in the biopsy core

Alicia G Aguilar Navarro et al. Br J Haematol. 2023 Mar.

Abstract

In their paper the authors describe distinct transcriptomic changes associated to treatment response in core bone marrow biopsies from patients with acute myeloid leukaemia. This finding raises the possibility that stratifying patients for treatment according to their transcriptomic profiles could improve patients' response and prognosis. Commentary on: Treaba et al. Transcriptomics of AML core bone marrow biopsies reveals distinct therapy response-specific osteo-mesenchymal profiles. Br J Haematol 2023;200:740-754.

Keywords: acute myeloid leukaemia; bone marrow; microenvironment.

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References

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