BCAT2-BCKDH metabolon maintains BCAA homeostasis

Miao Yin^{1

2}, Qun-Ying Lei^{3

4}

Affiliations

¹ Fudan University Shanghai Cancer Center & Institutes of Biomedical Sciences, Cancer Institutes, School of Basic Medical Sciences, Key Laboratory of Breast Cancer in Shanghai, Shanghai Key Laboratory of Radiation Oncology, The Shanghai Key Laboratory of Medical Epigenetics, Shanghai Medical College, Fudan University, Shanghai, China. miaoyin@fudan.edu.cn.
² Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. miaoyin@fudan.edu.cn.
³ Fudan University Shanghai Cancer Center & Institutes of Biomedical Sciences, Cancer Institutes, School of Basic Medical Sciences, Key Laboratory of Breast Cancer in Shanghai, Shanghai Key Laboratory of Radiation Oncology, The Shanghai Key Laboratory of Medical Epigenetics, Shanghai Medical College, Fudan University, Shanghai, China. qlei@fudan.edu.cn.
⁴ Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. qlei@fudan.edu.cn.

Comment

Miao Yin et al. Nat Metab. 2022 Dec.

. 2022 Dec;4(12):1618-1619.

doi: 10.1038/s42255-022-00680-z.

Miao Yin^{1

2}, Qun-Ying Lei^{3

4}

¹ Fudan University Shanghai Cancer Center & Institutes of Biomedical Sciences, Cancer Institutes, School of Basic Medical Sciences, Key Laboratory of Breast Cancer in Shanghai, Shanghai Key Laboratory of Radiation Oncology, The Shanghai Key Laboratory of Medical Epigenetics, Shanghai Medical College, Fudan University, Shanghai, China. miaoyin@fudan.edu.cn.
² Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. miaoyin@fudan.edu.cn.
³ Fudan University Shanghai Cancer Center & Institutes of Biomedical Sciences, Cancer Institutes, School of Basic Medical Sciences, Key Laboratory of Breast Cancer in Shanghai, Shanghai Key Laboratory of Radiation Oncology, The Shanghai Key Laboratory of Medical Epigenetics, Shanghai Medical College, Fudan University, Shanghai, China. qlei@fudan.edu.cn.
⁴ Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. qlei@fudan.edu.cn.

No abstract available

Comment on

Metabolon formation regulates branched-chain amino acid oxidation and homeostasis.
Patrick M, Gu Z, Zhang G, Wynn RM, Kaphle P, Cao H, Vu H, Cai F, Gao X, Zhang Y, Chen M, Ni M, Chuang DT, DeBerardinis RJ, Xu J. Patrick M, et al. Nat Metab. 2022 Dec;4(12):1775-1791. doi: 10.1038/s42255-022-00689-4. Epub 2022 Nov 28. Nat Metab. 2022. PMID: 36443523 Free PMC article.

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