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. 2023 Feb 18;38(2):205-212.
doi: 10.1093/arclin/acac088.

Unpacking the NIH Toolbox Emotion Battery in Persons With Parkinson's disease

Francesca V Lopez  1 , Rachel Schade  1 , Adrianna Ratajska  1 , Lauren Kenney  1 , Katie Rodriguez  1 , Alyssa Ray  1 , Lauren Santos  1 , Bonnie M Scott  1 , Erin Trifilio  1 , Dawn Bowers  1   2
Affiliations

Unpacking the NIH Toolbox Emotion Battery in Persons With Parkinson's disease

Francesca V Lopez et al. Arch Clin Neuropsychol. .

Abstract

Objective: Examine the relationship between the National Institutes of Health Toolbox Emotion Battery (Emotion Toolbox) and traditional measures in Parkinson's disease (PD).

Method: Persons with PD (n = 30) and cognitively healthy older adults (OA; n = 40) completed the Emotion Toolbox consisting of Well-Being, Negative Affect, and Social Satisfaction scores along with traditional measures of depression (Beck Depression Inventory-II [BDI-II]), anxiety (State-Trait Anxiety Inventory [STAI]), and apathy (Apathy Scale [AS]); total raw scores).

Results: Separate bootstrapped analyses of covariance indicated that the PD group scored higher on BDI-II and STAI-State compared to OA (ps < .01); groups did not differ on Emotion Toolbox. In the PD group, bootstrapped partial correlations indicated that Negative Affect was positively related to BDI-II and STAI (ps ≤ .001). Social Satisfaction was negatively related to BDI-II and STAI-Trait (.05 < ps < .004). Psychological Well-Being was negatively related to BDI-II, AS, and STAI (p < .004). No relationships emerged in OA. In the PD group, separate binary logistic regressions showed that traditional measures (BDI-II, AS, and STAI-Trait) correctly classified 79.6% those with formal psychiatric diagnoses (presence vs. absence; p < .011), whereas Emotion Toolbox measures correctly classified 73.3% (p < .019).

Conclusions: The Emotion Toolbox showed moderate-strong correlations with traditional measures in persons with PD. Even so, it did not capture the group differences between PD and OA and had a somewhat lower classification accuracy rate for persons with PD who had a formal psychiatric diagnosis than traditional measures. Together, findings question the utility of the Emotion Toolbox as a stand-alone emotion screener in PD.

Keywords: Computerized assessment; Emotion health; Parkinson’s disease.

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