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Review
. 2022 Jun;51(6):1232-1244.
doi: 10.18502/ijph.v51i6.9666.

Graft and Patient Survival Rate among Iranian Pediatric Recipients of Kidney Transplantation: A Systematic Review and Meta-Analysis

Ahmad Shajari  1 , Mohammad Moein Ashrafi  2 , Hamideh Shajari  3 , Ali Derakhshan  4
Affiliations
Review

Graft and Patient Survival Rate among Iranian Pediatric Recipients of Kidney Transplantation: A Systematic Review and Meta-Analysis

Ahmad Shajari et al. Iran J Public Health. 2022 Jun.

Abstract

Background: The End Stage Renal Disease (ESRD) is irreversible impairment of renal function, to the extent that the patient becomes permanently dependent on alternative therapies, especially in children. We aimed to evaluate the graft and patient survival rate among iranian pediatric recipients of kidney transplantation through a systematic review and meta-analysis.

Methods: National (SID, MagIran, IranMedex, IranDoc) and international (Cochrane, Embase, ScienceDirect, Scopus, PubMed, and Web of Science) databases of, were searched to find studies published electronically from 1985 until Nov 2019. Heterogeneity between the collected studies was determined using the Cochran's test (Q) and I2. Meta-regression was used to investigate the factors affecting statistical heterogeneity in 1, 5, and 10-year survival of kidney transplantation in addition to subgroup analysis based on cities.

Results: Ten studies were qualified to enter the meta-analysis. The total participants in the study were 2673 people with an average age of 13.71±3.65 years. In the random-effects model, the survival rate of 1, 3, 5 and 10 yr of kidney transplantation were 91, 88, 81 and 70%, respectively.

Conclusion: By providing the documented and comprehensive evidence, can be the basis of many plans, policies, and decisions of various sectors of development. These sectors include the evaluation of treatment programs and health interventions in the pediatric kidney transplantation. The results of the present study can provide an acceptable estimate of the survival rate of transplanted children in Iran and will be useful for planning prevention and treatment programs.

Keywords: End stage renal disease; Graft survival; Kidney transplantation; Meta-analysis; Patient survival.

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Figures

Fig. 1:
Fig. 1:
Flowchart of the included eligible studies in systematic review
Fig. 2:
Fig. 2:
A: 1-year Survival Rate of Iranian Pediatric Patients with Transplanted Kidney B: 2-year Survival Rate of Iranian Pediatric Patients with Transplanted Kidney
Fig. 3:
Fig. 3:
A: 3-year Survival Rate of Iranian Pediatric Patients with Transplanted Kidney, B: 5-year Survival Rate of Iranian Pediatric Patients with Transplanted Kidney
Fig. 4:
Fig. 4:
A: 7-year Survival Rate of Iranian Pediatric Patients with Transplanted Kidney, B: 10-year Survival Rate of Iranian Pediatric Patients with Transplanted Kidney
Fig. 5:
Fig. 5:
A: 1-year Survival Rate of Iranian Pediatric Patients with Transplanted Kidney by City, B: 5-year Survival Rate of Iranian Pediatric Patients with Transplanted Kidney by City
Fig. 6:
Fig. 6:
10-year Survival Rate of Iranian Pediatric Patients with Transplanted Kidney by City
See this image and copyright information in PMC

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References

    1. Ghelichi Ghojogh M, Taghizadeh Afshari A, Salarilak S, et al. (2017). The Effect of Body Mass Index on Patient and Graft Survival Rate in Kidney Transplanted Patients in Iran. Nephro-Urol Mon, 9(4): e14386.
    1. Ghelichi-Ghojogh M, Ghaem H, Mohammadizadeh F, et al. (2021). Graft and Patient Survival Rates in Kidney Transplantation, and Their Associated Factors: A Systematic Review and Meta-Analysis. Iran J Public Health, 50(8):1555–1563. - PMC - PubMed
    1. Naderi G, Latif A, Karimi S, et al. (2017). The long-term outcome of pediatric kidney transplantation in Iran: Results of a 25-year single-center cohort study. Int J Organ Transplant Med, 8(2):85–96 - PMC - PubMed
    1. Gheissari A, Hemmatzadeh S, Merrikhi A, et al. (2012). Chronic kidney disease in children: A report from a tertiary care center over 11 years. J Nephropathol, 1(3):177–82. - PMC - PubMed
    1. Einollahi B, Pourfarziani V, Ahmadzad-Asl M, et al. (2007). Iranian model of renal allograft transplantation in 3028 recipients: survival and risk factors. Transplant Proc, 39(4):907–10. - PubMed

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