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. 2023 Mar 1;94(3):385-391.
doi: 10.1097/TA.0000000000003844. Epub 2022 Nov 29.

Are we waiting for the sky to fall? Predictors of withdrawal of life-sustaining support in older trauma patients: A retrospective analysis

Affiliations

Are we waiting for the sky to fall? Predictors of withdrawal of life-sustaining support in older trauma patients: A retrospective analysis

Avanti Badrinathan et al. J Trauma Acute Care Surg. .

Abstract

Background: Limited data exist regarding the impact of advanced care planning for injured geriatric patients. We hypothesized that patients with advance directives limiting care (ADLC) compared with those without ADLC are more likely to undergo withdrawal of life-sustaining support (WLSS).

Methods: This is a propensity-matched analysis utilizing American College of Surgeons Trauma Quality Improvement Program patients 65 years or older who presented between 2017 and 2018. Patients with and without ADLC on admission were compared. The primary outcome was WLSS and days prior to WLSS. Additional factors examined included hospital length of stay (LOS), unplanned operations, unplanned intensive care unit admissions, and in-hospital cardiac arrests. Prior to matching, logistic regression model assessed factors associated with WLSS. Patients with and without ADLC were matched 1:1 via a propensity score using patient and injury factors as covariates, and matched pair analysis compared differences in WLSS between patients with and without ADLC.

Results: There were 597,840 patients included: 44,001 patients with an ADLC (7.36%) compared with 553,839 with no ADLC (92.64%). Patients with an ADLC underwent WLSS more often than those with no ADLC (7.68% vs. 2.48%, p < 0.001). In a 1:1 propensity-matched analysis, patients with ADLC were more likely to undergo WLSS (odds ratio [OR], 2.38' 95% confidence interval [CI], 2.22-2.55), although stronger predictors of WLSS included severity of injury (Injury Severity Score, 25+; OR, 23.84; 95% CI, 21.55-26.36), unplanned intensive care unit admissions (OR, 3.30; 95% CI, 2.89-3.75), and in-hospital cardiac arrests (OR, 4.97; 95% CI, 4.02-6.15).

Conclusion: A small proportion of the geriatric trauma population had ADLC on admission. While ADLC was predictive of WLSS, adverse events were more strongly associated with WLSS. To ensure patient-centered care and reduce futile interventions, surgeons should delineate goals of care early regardless of ADLC.

Level of evidence: Therapeutic/Care Management; Level III.

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Conflict of interest statement

Conflict of interests:

VPH’s spouse is a consultant for Atricure, Zimmer Biomet, Sig Medical and Medtronic, but these relationships have not influenced this work in any way.

Figures

Figure 1:
Figure 1:
Flowchart of study design
Figure 2:
Figure 2:
Graph of standardized differences before and after propensity match

References

    1. Hashmi A, Ibrahim-Zada I, Rhee P, Aziz H, Fain MJ, Friese RS, et al. Predictors of mortality in geriatric trauma patients: a systematic review and meta-analysis. J Trauma Acute Care Surg. 2014;76(3):894–901. - PubMed
    1. Gioffrè-Florio M, Murabito LM, Visalli C, Pergolizzi FP, Famà F. Trauma in elderly patients: a study of prevalence, comorbidities and gender differences. G Chir. 2018;39(1):35–40. - PMC - PubMed
    1. Suwanabol PA, Li Y, Abrahamse P, De Roo AC, Vu JV, Silveira MJ, et al. Functional and Cognitive Decline Among Older Adults After High-risk Surgery. Ann Surg. 2022;275(1):e132–e139. - PMC - PubMed
    1. Yadav KN, Gabler NB, Cooney E, Kent S, Kim J, Herbst N, et al. Approximately One In Three US Adults Completes Any Type Of Advance Directive For End-Of-Life Care. Health Affairs. 2017;36(7):1244–1251. - PubMed
    1. Jawa RS, Shapiro MJ, McCormack JE, Huang EC, Rutigliano DN, Vosswinkel JA. Preadmission Do Not Resuscitate advanced directive is associated with adverse outcomes following acute traumatic injury. Am J Surg. 2015;210(5):814–821. - PubMed

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