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Comment
. 2023 Mar 1;207(5):626-628.
doi: 10.1164/rccm.202211-2091LE.

Did Balanced Crystalloids Really Decrease Mortality in Patients with Sepsis?

Gildas Gueret  1
Affiliations
Comment

Did Balanced Crystalloids Really Decrease Mortality in Patients with Sepsis?

Gildas Gueret. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
Percentage of mortality, type of admission, and vasopressor use according to group. Two groups are presented (BC only + mix, saline only + no fluid). BC = balanced crystalloids.
Figure 2.
Figure 2.
Relationship between mortality and the type of admission according to Table E2 in Zampieri and colleagues (1). This figure shows the strong relationship between mortality and the type of admission. BS = balanced solution; NS = normale saline.
See this image and copyright information in PMC

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References

    1. Zampieri FG, Machado FR, Biondi RS, Freitas FGR, Veiga VC, Figueiredo RC, et al. Association between type of fluid received prior to enrollment, type of admission, and effect of balanced crystalloid in critically ill adults: a secondary exploratory analysis of the BaSICS clinical trial. Am J Respir Crit Care Med . 2022;205:1419–1428. - PubMed
    1. Zampieri FG, Machado FR, Biondi RS, Freitas FGR, Veiga VC, Figueiredo RC, et al. BaSICS investigators and the BRICNet members Effect of intravenous fluid treatment with a balanced solution vs 0.9% saline solution on mortality in critically ill patients: the BaSICS randomized clinical trial. JAMA . 2021;326:818–829. - PMC - PubMed
    1. Semler MW, Self WH, Wanderer JP, Ehrenfeld JM, Wang L, Byrne DW, et al. SMART Investigators and the Pragmatic Critical Care Research Group Balanced crystalloids versus saline in critically ill adults. N Engl J Med . 2018;378:829–839. - PMC - PubMed
    1. Jackson KE, Wang L, Casey JD, Bernard GR, Self WH, Rice TW, et al. SMART Investigators and the Pragmatic Critical Care Research Group Effect of early balanced crystalloids before ICU admission on sepsis outcomes. Chest . 2021;159:585–595. - PMC - PubMed
    1. Tseng CH, Chen TT, Wu MY, Chan MC, Shih MC, Tu YK. Resuscitation fluid types in sepsis, surgical, and trauma patients: a systematic review and sequential network meta-analyses. Crit Care . 2020;24:693. - PMC - PubMed