Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2023 Mar 1;207(5):628-629.
doi: 10.1164/rccm.202211-2127LE.

Reply to Gueret: Did Balanced Crystalloids Really Decrease Mortality in Patients with Sepsis?

Fernando G Zampieri  1   2   3 , Flavia R Machado  2   3 , Alexandre B Cavalcanti  1   2
Affiliations
Comment

Reply to Gueret: Did Balanced Crystalloids Really Decrease Mortality in Patients with Sepsis?

Fernando G Zampieri et al. Am J Respir Crit Care Med. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Left: Box plot for Sequential Organ Failure Assessment (SOFA) score according to randomization arm. Right: SOFA score according to fluid group as in Reference and intervention.
See this image and copyright information in PMC

Comment on

References

    1. Zampieri FG, Machado FR, Biondi RS, Freitas FGR, Veiga VC, Figueiredo RC, et al. Association between type of fluid received prior to enrollment, type of admission, and effect of balanced crystalloid in critically ill adults: a secondary exploratory analysis of the BaSICS clinical trial. Am J Respir Crit Care Med . 2022;205:1419–1428. - PubMed
    1. Alosh M, Fritsch K, Huque M, Mahjoob K, Pennello G, Rothmann M, et al. Statistical considerations on subgroup analysis in clinical trials. Stat Biopharm Res . 2015;7:286–303.
    1. Hammond NE, Zampieri FG, Di Tanna GL, Garside T, Adigbli D, Cavalcanti AB, et al. Balanced crystalloids versus saline in critically ill adults—a systematic review with meta-analysis. NEJM Evid . 2022;1 - PubMed
    1. Zampieri FG, Cavalcanti AB, Di Tanna GL, Damiani LP, Hammond NE, Machado FR, et al. Statistical Analysis Plan for Balanced versus Saline trialists living systematic review individual patient and aggregated data meta-analysis of randomized controlled trials (BEST-Living Study) [preprint] medRxiv . doi: 10.1101/2022.09.06.22279363. - DOI - PMC - PubMed

Substances