Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Oct;74(Suppl 2):2071-2075.
doi: 10.1007/s12070-020-02011-8. Epub 2020 Aug 3.

Core Needle Biopsy in Suspicious Malignant Thyroid Nodules with Repeated Nondiagnostic Fine Needle Aspiration

Farrokh Heidari  1 , Firouzeh Heidari  1 , Mohammad Sadeq Najafi  1 , Reza Ansari  1 , Kayvan Aghazadeh  1 , Saeed Sohrabpour  1 , Ebrahim Karimi  1
Affiliations

Core Needle Biopsy in Suspicious Malignant Thyroid Nodules with Repeated Nondiagnostic Fine Needle Aspiration

Farrokh Heidari et al. Indian J Otolaryngol Head Neck Surg. 2022 Oct.

Abstract

Key message: The clinician could have CNB in mind for thyroid nodules when FNA results were nondiagnostic. Our study would suggest CNB a safe and efficient method for investigating thyroid nodules.

Abstract: Usefulness of preoperative tissue sampling and pathology diagnoses in thyroid tumors were accepted worldwide. We investigate the role of Core needle biopsy (CNB) in the thyroid nodules lesions when FNA results are nondiagnostic. We conducted a cross-sectional study to evaluate twenty-six CNBs results of suspicious malignant thyroid nodules with nondiagnostic repeated fine needle aspiration. 25 from 26 CNBs were diagnostic. Twenty-one needle biopsy reports were papillary thyroid carcinoma, three CNB samples diagnosed medullary thyroid carcinoma and one of them had anaplastic results. All diagnostic needle biopsies results were compatible with final pathology. Our study would suggest CNB a safe and efficient method for investigating thyroid nodules while repeated FNA yielded nondiagnostic results.

Keywords: Core needle biopsy; Nondiagnostic fine needle aspiration; Thyroid cancer; Thyroid nodules; Tissue sampling.

PubMed Disclaimer

Conflict of interest statement

Conflict of interestThe authors declare that there are no conflicts of interest.

References

    1. Cibas ES, Ali SZ. The 2017 Bethesda system for reporting thyroid cytopathology. Thyroid. 2017;27(11):1341–1346. doi: 10.1089/thy.2017.0500. - DOI - PubMed
    1. Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, Pacini F, Randolph GW, Sawka AM, Schlumberger M, Schuff KG, Sherman SI, Sosa JA, Steward DL, Tuttle RM, Wartofsky L. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016;26(1):1–133. doi: 10.1089/thy.2015.0020. - DOI - PMC - PubMed
    1. Baek JH. Current status of core needle biopsy of the thyroid. Ultrasonography. 2017;36(2):83–85. doi: 10.14366/usg.17018. - DOI - PMC - PubMed
    1. Jung CK, Hong S, Bychkov A, Kakudo K. The use of fine-needle aspiration (FNA) cytology in patients with thyroid nodules in Asia: a brief overview of studies from the working group of Asian thyroid FNA cytology. J Pathol Transl Med. 2017;51(6):571–578. doi: 10.4132/jptm.2017.10.19. - DOI - PMC - PubMed
    1. Wang C, Vickery AL, Jr, Maloof F. Needle biopsy of the thyroid. Surg Gynecol Obstet. 1976;143(3):365–368. - PubMed

LinkOut - more resources