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. 2022 Oct;74(Suppl 2):2331-2333.
doi: 10.1007/s12070-020-02161-9. Epub 2020 Sep 25.

Laryngeal Dysplasia: To Biopsy or Not?

Reshmi Anna Alex  1 , Suma Susan Mathews  1 , Roshna Rose Paul  1 , Rita Ruby A Albert  1
Affiliations

Laryngeal Dysplasia: To Biopsy or Not?

Reshmi Anna Alex et al. Indian J Otolaryngol Head Neck Surg. 2022 Oct.

Abstract

A renal transplant recipient with chronic hepatitis B underwent multiple laser excisions over 4 years for laryngeal keratosis. From the initial histopathology reports of mild to moderate dysplasia, a progression to squamous carcinoma was noted over 4 years. This case report highlights the possible role of immunosuppressants and hepatitis virus in the aetiopathogenesis of laryngeal carcinoma.

Keywords: Biopsy; Dysplasia; Follow up, immunosuppressants; Keratosis larynx.

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Conflict of interest statement

Conflict of interestThe author declares that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Mild grade dysplasia -Epithelial hyperplasia and keratosis with disordered maturation
Fig. 2
Fig. 2
a Pre-operative image-Keratotic lesion involving the supero-medial surface of the anterior two third of bilateral true vocal cords. b Invasive squamous cell carcinoma—Moderate nuclear pleomorphism, dyskeratosis, mitosis, keratin pearl formation, atypia
See this image and copyright information in PMC

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