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. 2023 Jun;18(6):1257-1258.
doi: 10.4103/1673-5374.360167.

Plasticity of callosal neurons in the contralesional cortex following traumatic brain injury

Alexandra Chovsepian  1 , Laura Empl  1 , Florence M Bareyre  2
Affiliations

Plasticity of callosal neurons in the contralesional cortex following traumatic brain injury

Alexandra Chovsepian et al. Neural Regen Res. 2023 Jun.
No abstract available

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Conflict of interest statement

None

Figures

Figure 1
Figure 1
Contralesional changes in spines and in circuit structure and function following traumatic brain injury. (A) Selective spine dynamics & morphology in callosal and non callosal neurons. (i) Schematic of the imaging performed in the contralesional cortex to investigate changes in spine dynamics and morphology. (ii) Schematic of the spine density in callosal (top) and non callosal (bottom) neurons following injury. (iii) Schematic of the quantification of spine density following injury. (iv) Schematic of the quantification of spine morphological subtypes following injury. (v) Schematic of the persistence index of the callosal and non callosal neurons. (B) Structural and functional circuit adaption of callosal neurons after injury. (i) Schematic of the imaging performed to determine structural adaptation of pre-synaptic input to callosal neurons. (ii) Structural adaptations of pre-synaptic input at early and late post-injury time points. (iii) Functional adaptations of callosal neurons following traumatic brain injury. (iv) Piechart showing the activity history of callosal neurons. Unpublished data.
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References

    1. Bradnam LV, Stinear CM, Barber PA, Byblow WD. Contralesional hemisphere control of the proximal paretic upper limb following stroke. Cereb Cortex. 2012;22:2662–2671. - PMC - PubMed
    1. Celeghin A, Diano M, de Gelder B, Weiskrantz L, Marzi CA, Tamietto M. Intact hemisphere and corpus callosum compensate for visuomotor functions after early visual cortex damage. Proc Natl Acad Sci U S A. 2017;114:E10475–10483. - PMC - PubMed
    1. Dodd KC, Nair VA, Prabhakaran V. Role of the contralesional vs. ipsilesional hemisphere in stroke recovery. Front Hum Neurosci. 2017;11:469. - PMC - PubMed
    1. Empl L, Chovsepian A, Chahin M, Kan WYV, Fourneau J, Van Steenbergen V, Weidinger S, Marcantoni M, Ghanem A, Bradley P, Conzelmann KK, Cai R, Ghasemigharagoz A, Ertürk A, Wagner I, Kreutzfeldt M, Merkler D, Liebscher S, Bareyre FM. Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury. Nat Commun. 2022;13:2659. - PMC - PubMed
    1. Hinkley LB, Marco EJ, Brown EG, Bukshpun P, Gold J, Hill S, Findlay AM, Jeremy RJ, Wakahiro ML, Barkovich AJ, Mukherjee P, Sherr EH, Nagarajan SS. The contribution of the corpus callosum to language lateralization. J Neurosci. 2016;36:4522–4533. - PMC - PubMed