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Comparative Study
. 1978 Sep;25(2):173-7.

An immunisation model for the control of infectious enteritis

  • PMID: 364577
Comparative Study

An immunisation model for the control of infectious enteritis

A J Husband. Res Vet Sci. 1978 Sep.

Abstract

An intestinal immunisation procedure involving systemic priming and oral boosting was investigated in lambs with a view to providing vaccination control of enteritis in young animals. The procedure stimulated the appearance of antibody-containing cells of IgA specificity in the intestine and lambs immunised in this way with a bacterial vaccine were protected against subsequent challenge with live enteropathogenic bacteria. This immunisation regime therefore provides a useful method for the stimulation of IgA immunity in the intestine of ruminants and it is anticipated that it will have general application to a variety of enteric diseases.

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