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. 2022 Nov 7;18(6):1678-1682.
doi: 10.5114/aoms/155114. eCollection 2022.

A comparison of the protective effect of vaccination and clinical features between the SARS-CoV-2 wild-type strain and Delta (B.1.617.2) variant

Yanzi Li  1 , Zhi Wang  2 , Junhui Liu  3 , Jianfeng Han  4 , Lin Yang  4   5
Affiliations

A comparison of the protective effect of vaccination and clinical features between the SARS-CoV-2 wild-type strain and Delta (B.1.617.2) variant

Yanzi Li et al. Arch Med Sci. .

Abstract

Introduction: This study aimed to investigate the clinical features and vaccine effectiveness of patients with the SARS-CoV-2 wild-type strain and the Delta variant.

Methods: We retrospectively evaluated patients with the SARS-CoV-2 wild-type strain and the Delta variant.

Results: The Delta-variant group showed a higher infection rate in minors, who had higher incidence of anosmia or dysgeusia and shorter incubation period. Unvaccinated patients had a 15.59-fold higher risk of severe classification than vaccinated patients. The viral clearance time was significantly shorter in the Delta-variant group.

Conclusions: The Delta-variant group show higher transmissibility, and vaccination reduces the incidence of severe classification and promotes viral clearance.

Keywords: COVID-19; SARS-CoV-2; clinical feature; pandemic; transmission; vaccine.

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Conflict of interest statement

The authors declare no conflict of interest.

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