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. 1978 Apr;134(4):277-86.

[Creutzfeldt Jakob disease. Recommended precautions for patient management and diagnostic procedures (author's transl)]

[Article in French]
P Brown, F Cathala, D C Gajdusek
  • PMID: 364589

[Creutzfeldt Jakob disease. Recommended precautions for patient management and diagnostic procedures (author's transl)]

[Article in French]
P Brown et al. Rev Neurol (Paris). 1978 Apr.

Abstract

The virus of Creutzfeldt Jakob disease differs from conventional viruses in its extraordinary resistance to commonly used physical and chemical methods of decontamination. Autoclaving the virus for 1 hour at 121 degrees C and 2 atmospheres pressure is the most certain means for achieving total inactivation. Exposure to 5 p. 100 hypochlorite for several hours can also totally inactivate the virus, and exposure to phenol or potassium permanganate is probably effective, but as yet insufficiently tested.

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