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Multicenter Study
. 2022 Dec 2;51(1):7.
doi: 10.1007/s00240-022-01382-7.

Validation of the Italian version of wisconsin stone quality of life (WISQOL): a prospective Italian multicenter study

Giorgio Mazzon  1 , Emanuele Serafin  2 , Stefania Ferretti  3 , Francesco Claps  4 , Wen Zhong  5 , Cristian Fiori  6 , Giuseppe Celentano  7 , Giulio Gaetano Guarino  3 , Davide Zamengo  6 , Andrea Piasentin  4 , Massimiliano Creta  7 , Nicola Longo  7 , Roberta Dordoni  3 , Nicola Pavan  4 , Claudio Brancelli  2 , Maria Angela Cerruto  2 , Alessandro Antonelli  2 , Antonio Celia  8
Affiliations
Multicenter Study

Validation of the Italian version of wisconsin stone quality of life (WISQOL): a prospective Italian multicenter study

Giorgio Mazzon et al. Urolithiasis. .

Abstract

Urolithiasis is a worldwide spread condition that affects patients' Health-Related Quality of Life (HRQOL), which measurement is an important tool for routine clinical and research practice. Disease-specific HRQOL measures demonstrated to perform better in assessing the effects of specific conditions. A disease-specific questionnaire for kidney stones, the WISQOL, has been validated in different languages, but an Italian version is still missing. Our aim is to produce and validate the Italian version of WISQOL (IT-WISQOL). Patients undergoing any elective treatment for upper urinary tract stones were enrolled. A multi-step process with forward- and back-translation was used to translate WISQOL into Italian. Patients were evaluated within 15 days pre-operatively and then at 30-, 90 days post-operatively and administered both IT-WISQOL and SF-36v2. Post-operative data such as 30 days postoperative complications, late stone-related events, successful status, and stone complexity were collected. Cronbach's α was used to evaluate the internal consistency of IT-WISQOL, while Spearman's rho was used for item and inter-domain correlations and IT-WISQOL with SF-36v2 correlation. We found excellent internal consistency across all domains (α ≥ 0.88), particularly when the total score is considered (α = 0.960). Test-retest reliability showed excellent results for the total questionnaire (Pearson correlation value: 0.85). The Inter-domain association ranged from 0.497 to 0.786. Convergent validity was confirmed by a good correlation with subdomains of the SF-36v2 measures. IT-WISQOL is a reliable tool to measure HRQOL in stone patients. It shows analog characteristics if compared to English WISQOL.

Keywords: Health-related quality of life; Kidney stones; Questionnaire; SF-36v2; Urolithiasis; WISQOL.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Correlation of WISQOL and SF-36v2 a Preoperative; b 30 days postoperative; c 3 months postoperative. Min–Max of IT-WISQOL score is 28–140 respectively
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